Compound
N-hexadecanoylsphing-4-enine
A N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl).
Definition from ChEBI (CHEBI:72959), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C34H67NO3
- Mass
- 537.914 g/mol
- Charge
- 0
- InChIKey
- YDNKGFDKKRUKPY-TURZORIXSA-N
- SMILES
- CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- CERT1ProteinUNIPROT:Q9Y5P4transported byInferred only47 paths47 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only26 paths26 endpoints
- GBA1ProteinUNIPROT:P04062substrate ofInferred only16 paths16 endpoints
- CERKProteinUNIPROT:Q8TCT0substrate ofInferred only12 paths12 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- NAAAProteinUNIPROT:Q02083substrate ofInferred only6 paths3 endpoints
- ACER2ProteinUNIPROT:Q5QJU3substrate ofInferred only4 paths4 endpoints
What the reference databases state
Chemical structure
- N-hexadecanoylsphing-4-enine has the functional parent hexadecanoic acidCompoundChEBI CHEBI:72959Inferred only
Statements
9 statements
9 statements · 2 reference databases · Subject: N-hexadecanoylsphing-4-enine · Sources: Human-GEM, Rhea
- N-hexadecanoylsphing-4-enine is converted to N-(hexadecanoyl)-sphing-4-enine-1-phosphateCompoundRhea RHEA:46340Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of ACER2ProteinRhea RHEA:38891Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of ASAH1ProteinRhea RHEA:38891Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of ASAH2ProteinRhea RHEA:38891Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of CERKProteinRhea RHEA:46340Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of GBA1ProteinRhea RHEA:58316Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of NAAAProteinRhea RHEA:38891Inferred only
- N-hexadecanoylsphing-4-enine is a substrate of NAAAProteinHuman-GEM MAR20096Inferred only
- N-hexadecanoylsphing-4-enine is transported by CERT1ProteinRhea RHEA:45720Inferred only
Reactions
10 reactions
water+N-hexadecanoylsphing-4-eninehexadecanoic acid+sphing-4-enine
Catalysed by NAAA
Reaction pageLeft to rightBalancedEC 3.5.1.23cytosol, nucleus
Human-GEM MAR20096CC BY 4.0Reference data
sphing-4-enine+hexadecanoyl-CoAN-hexadecanoylsphing-4-enine+coenzyme A(4-)+hydron
Catalysed by CERS6 or TLCD3B or CERS5 or CERS2
Reaction pageLeft to rightBalanced
Rhea RHEA:36687CC BY 4.0Reference data
N-hexadecanoylsphing-4-enine+watersphing-4-enine+hexadecanoate
Catalysed by NAAA or ASAH1 or ACER2 or ASAH2
Reaction pageReversibleBalanced
Rhea RHEA:38891CC BY 4.0Reference data
N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine+waterN-hexadecanoylsphing-4-enine+phosphocholine+hydron
Catalysed by SMPD3
Reaction pageLeft to rightBalanced
Rhea RHEA:45644CC BY 4.0Reference data
N-hexadecanoylsphing-4-enineN-hexadecanoylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:45720CC BY 4.0Reference data
N-hexadecanoylsphing-4-enine+ATP(4-)N-(hexadecanoyl)-sphing-4-enine-1-phosphate+ADP(3-)+hydron
Catalysed by CERK
Reaction pageLeft to rightBalanced
Rhea RHEA:46340CC BY 4.0Reference data
beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine+CHEBI:142575CHEBI:142576+N-hexadecanoylsphing-4-enine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:58296CC BY 4.0Reference data
beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine+cholesterolcholesteryl 3-beta-D-glucoside+N-hexadecanoylsphing-4-enine
Catalysed by GBA1
Reaction pageReversibleBalanced
Rhea RHEA:58316CC BY 4.0Reference data
beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine+waterN-hexadecanoylsphing-4-enine+beta-D-glucose
Catalysed by LCT
Reaction pageLeft to rightBalanced
Rhea RHEA:69699CC BY 4.0Reference data
beta-D-galactosyl-(1<->1')-N-hexadecanoylsphing-4-enine+waterbeta-D-galactose+N-hexadecanoylsphing-4-enine
Catalysed by LCT
Reaction pageLeft to rightBalanced
Rhea RHEA:69703CC BY 4.0Reference data
Where it reaches
8 systems, 19 regions, 42 tissues, 42 transporter routes — routes, not measurements: transporters known to carry N-hexadecanoylsphing-4-enine are expressed there, and no source reports it arriving.
Loading the model…
Other names
21 names
Resolves to: N-hexadecanoylsphing-4-enine
- Also called
- (2S,3R,4E)-2-acylamino-1,3-octadec-4-enediol(2S,3R,4E)-2-acylaminooctadec-4-ene-1,3-diolC16 CerC16 CeramideC16-0(Palmitoyl)ceramideCer 34:1;O2Cer(d18:1(4E)/16:0)Cer(d18:1/16:0)Cer[NS]Ceramide (d18:1/16:0)N-(hexadecanoyl)-ceramideN-(hexadecanoyl)-sphing-4-enineN-(hexadecanoyl)ceramideN-(hexadecanoyl)sphing-4-enineN-(palmitoyl)-ceramideN-(palmitoyl)ceramideN-hexadecanoyl-D-erythro-sphingosineN-palmitoyl-sphingosineN-palmitoylsphing-4-enineN-palmitoylsphingosine
- Systematic name
- N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]hexadecanamide