Compound
2-hydroxyhexadecanoyl-CoA
An acyl-CoA(4−) arising from deprotonation of the phosphate and diphosphate functions of 2-hydroxypalmitoyl-CoA.
Definition from ChEBI (CHEBI:74115), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C37H62N7O18P3S
- Mass
- 1017.923 g/mol
- Charge
- -4
- InChIKey
- KCYAHSOGWAZYJF-QGGHQSAPSA-J
- SMILES
- CCCCCCCCCCCCCCC(O)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: 2-hydroxyhexadecanoyl-CoA · Sources: Rhea
- hexadecanoyl-CoA is converted to 2-hydroxyhexadecanoyl-CoACompoundRhea RHEA:54596Inferred only
- 2-hydroxyhexadecanoyl-CoA is a substrate of CERS5ProteinRhea RHEA:36647Inferred only
Reactions
3 reactions
2-hydroxyhexadecanoyl-CoA+sphinganineN-(2-hydroxyhexadecanoyl)-sphinganine+coenzyme A(4-)+hydron
Catalysed by CERS5
Reaction pageLeft to rightBalanced
Rhea RHEA:36647CC BY 4.0Reference data
CHEBI:65097+ATP(4-)+coenzyme A(4-)2-hydroxyhexadecanoyl-CoA+AMP+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:44204CC BY 4.0Reference data
hexadecanoyl-CoA+2-oxoglutarate(2-)+dioxygen2-hydroxyhexadecanoyl-CoA+succinate(2-)+carbon dioxide
Catalysed by PHYH
Reaction pageLeft to rightBalanced
Rhea RHEA:54596CC BY 4.0Reference data
Other names
13 names
Resolves to: 2-hydroxyhexadecanoyl-CoA
- Also called
- 2-hydroxy-C16:0-CoA(4-)2-hydroxy-C16:0-CoA(4−)2-hydroxyhexadecanoyl-CoA(4-)2-hydroxyhexadecanoyl-CoA(4−)2-hydroxyhexadecanoyl-coenzyme A(4-)2-hydroxyhexadecanoyl-coenzyme A(4−)2-hydroxypalmitoyl-coenzyme A(4-)2-hydroxypalmitoyl-coenzyme A(4−)2-OH-C16:0-CoA(4-)2-OH-C16:0-CoA(4−)2-OH-palmitoyl-CoA(4-)2-OH-palmitoyl-CoA(4−)
- Systematic name
- 3'-phosphonatoadenosine 5'-{3-[(3R)-3-hydroxy-4-{[3-({2-[(2-hydroxyhexadecanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-2,2-dimethyl-4-oxobutyl] diphosphate}