Compound
3-oxosphinganine
A cationic sphingoid that is the conjugate acid of 3-dehydrosphinganine; major species at pH 7.3.
Definition from ChEBI (CHEBI:58299), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, cation
- Formula
- C18H38NO2
- Mass
- 300.507 g/mol
- Charge
- +1
- InChIKey
- KBUNOSOGGAARKZ-KRWDZBQOSA-O
- SMILES
- CCCCCCCCCCCCCCCC(=O)[C@@H]([NH3+])CO
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
1 entity
1 entities reached.
0 reported hops1 assembled from the scaffold
What the reference databases state
Statements
5 statements
5 statements · 2 reference databases · Subject: 3-oxosphinganine · Sources: Human-GEM, Rhea
- 3-oxosphinganine is converted to CHEBI:16566CompoundHuman-GEM MAR00741Inferred only
- hexadecanoyl-CoA is converted to 3-oxosphinganineCompoundRhea RHEA:14761Inferred only
- 3-oxosphinganine is converted to sphinganineCompoundRhea RHEA:22640Inferred only
- 3-oxosphinganine is a substrate of KDSRProteinHuman-GEM MAR00741Inferred only
- 3-oxosphinganine is a substrate of KDSRProteinRhea RHEA:22640Inferred only
Reactions
15 reactions
proton+palmitoyl-CoA+L-seryl residue3-oxosphinganine+carbon dioxide+CHEBI:1146900
Catalysed by SPTLC1 & SPTLC2 & SPTLC3
Reaction pageLeft to rightBalancedEC 2.3.1.50cytosol
Human-GEM MAR00738CC BY 4.0Reference data
3-oxosphinganine+proton+NADPH(4-)NADP(3-)+CHEBI:16566
Catalysed by KDSR
Reaction pageLeft to rightBalancedEC 1.1.1.102cytosol
Human-GEM MAR00741CC BY 4.0Reference data
L-seryl residue+hexadecanoyl-CoA+hydron3-oxosphinganine+carbon dioxide+coenzyme A(4-)
Catalysed by SPTLC1 or SPTLC2 or SPTLC3
Reaction pageLeft to rightBalanced
Rhea RHEA:14761CC BY 4.0Reference data
sphinganine+NADP(3-)3-oxosphinganine+NADPH(4-)+hydron
Catalysed by KDSR
Reaction pageRight to leftBalanced
Rhea RHEA:22640CC BY 4.0Reference data
3-oxosphinganine+a fatty acyl-CoACHEBI:189535+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:70359CC BY 4.0Reference data
3-oxosphinganine+octanoyl-CoACHEBI:189539+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70367CC BY 4.0Reference data
3-oxosphinganine+decanoyl-CoACHEBI:189538+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70371CC BY 4.0Reference data
3-oxosphinganine+dodecanoyl-CoACHEBI:189537+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70375CC BY 4.0Reference data
3-oxosphinganine+tetradecanoyl-CoACHEBI:189536+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70379CC BY 4.0Reference data
3-oxosphinganine+hexadecanoyl-CoACHEBI:189534+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70383CC BY 4.0Reference data
3-oxosphinganine+octadecanoyl-CoACHEBI:189540+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70387CC BY 4.0Reference data
3-oxosphinganine+eicosanoyl-CoACHEBI:189541+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:70391CC BY 4.0Reference data
Other names
4 names
Resolves to: 3-oxosphinganine
- Also called
- 3-dehydro-D-sphinganine3-dehydrosphinganinium3-dehydrosphinganinium cation
- Systematic name
- (2S)-1-hydroxy-3-oxooctadecan-2-aminium