an L-alpha-amino acid

1. Xaa-L-Pro dipeptide + H2O = an L-alpha-amino acid + L-proline

Catalysed by PEPD

1. an L-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4(+)

Catalysed by IL4I1

1. an L-alpha-amino acid(in) + L-kynurenine(out) = an L-alpha-amino acid(out) + L-kynurenine(in)

Catalysed by SLC7A11inner side of the membrane, outer side of the membraneOne of 2 routes

1. an N-acyl-L-amino acid + H2O = an L-alpha-amino acid + a carboxylate

Catalysed by ACY1, PM20D1

1. an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid

Catalysed by DPEP1, DPEP2

1. an L-alpha-amino acid(in) + L-kynurenine(out) = an L-alpha-amino acid(out) + L-kynurenine(in)
2. Transport of L-Kynurenine

Catalysed by SLC7A11, SLC43A1inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 3 routes

1. an L-alpha-amino acid(in) + L-kynurenine(out) = an L-alpha-amino acid(out) + L-kynurenine(in)
2. L-kynurenine + H2O = anthranilate + L-alanine + H(+)

Catalysed by SLC7A11, KYNUinner side of the membrane, outer side of the membrane

1. an L-alpha-amino acid(in) + L-kynurenine(out) = an L-alpha-amino acid(out) + L-kynurenine(in)
2. indole-3-pyruvate + L-kynurenine = kynurenate + L-tryptophan + H2O
3. beta-carboline hydrolysis

Catalysed by SLC7A11, AADATinner side of the membrane, outer side of the membrane, cytosol

1. an L-alpha-amino acid(in) + L-kynurenine(out) = an L-alpha-amino acid(out) + L-kynurenine(in)
2. L-Kynurenine hydrolase
3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

Catalysed by SLC7A11