Compound

L-2-aminoadipate

Conjugate base of L-2-aminoadipic acid.

Definition from ChEBI (CHEBI:58672), read 2026-09-23. CC BY 4.0.

CHEBI:58672ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of L-2-aminoadipate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H10NO4
Mass: 160.149 g/mol
Charge: -1
InChIKey: OYIFNHCXNCRBQI-BYPYZUCNSA-M
SMILES: [NH3+][C@@H](CCCC(=O)[O-])C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

AADATProteinUNIPROT:Q8N5Z0substrate ofInferred only20 paths10 endpoints

What the reference databases state

Statements

9 statements

9 statements · 1 reference database · Subject: L-2-aminoadipate · Sources: Rhea

Order

(S)-2-amino-6-oxohexanoate is converted to L-2-aminoadipateCompoundRhea RHEA:46936Inferred only
L-2-aminoadipate is converted to (S)-2-amino-6-oxohexanoateCompoundRhea RHEA:46936Inferred only
L-2-aminoadipate is converted to (S)-2-amino-6-oxohexanoateCompoundRhea RHEA:12304Inferred only
(S)-2-amino-6-oxohexanoate is converted to L-2-aminoadipateCompoundRhea RHEA:12304Inferred only
(S)-2-amino-6-oxohexanoate is converted to L-2-aminoadipateCompoundRhea RHEA:12308Inferred only
L-2-aminoadipate is converted to 2-oxoadipateCompoundRhea RHEA:12601Inferred only
L-2-aminoadipate is a substrate of AADATProteinRhea RHEA:12601Inferred only
L-2-aminoadipate is a substrate of AADATProteinRhea RHEA:69112Inferred only
L-2-aminoadipate is transported by SLC25A21ProteinRhea RHEA:71747Inferred only

Reactions

15 reactions

(S)-2-amino-6-oxohexanoate+NADP(3-)+waterL-2-aminoadipate+NADPH(4-)+2hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:12304CC BY 4.0Reference data
(S)-2-amino-6-oxohexanoate+NAD(1-)+waterL-2-aminoadipate+NADH(2-)+2hydron
Catalysed by ALDH7A1
Reaction pageLeft to rightBalanced
Rhea RHEA:12308CC BY 4.0Reference data
L-2-aminoadipate+2-oxoglutarate(2-)2-oxoadipate+L-glutamate(1-)
Catalysed by AADAT
Reaction pageLeft to rightBalanced
Rhea RHEA:12601CC BY 4.0Reference data
CHEBI:58399+phenylacetyl-CoA+waterCHEBI:51354+L-2-aminoadipate+coenzyme A(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:20720CC BY 4.0Reference data
L-2-aminoadipate+L-valine+L-cysteine+3ATP(4-)+waterCHEBI:58572+3AMP+3diphosphate(3-)+3hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:23196CC BY 4.0Reference data
[amino-group carrier protein]-C-terminal-L-glutamate+L-2-aminoadipate+ATP(4-)[amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:41940CC BY 4.0Reference data
(S)-2-amino-6-oxohexanoate+AMP+diphosphate(3-)+NADP(3-)L-2-aminoadipate+ATP(4-)+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:46936CC BY 4.0Reference data
L-2-aminoadipyl-[LYS2 peptidyl-carrier protein]+AMP+diphosphate(3-)holo-[LYS2 peptidyl-carrier protein]+L-2-aminoadipate+ATP(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:46940CC BY 4.0Reference data
CHEBI:58769+NAD(1-)+2waterL-2-aminoadipate+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:49476CC BY 4.0Reference data
CHEBI:58769+NADP(3-)+2waterL-2-aminoadipate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:49480CC BY 4.0Reference data
L-2-aminoadipate+glyoxylate2-oxoadipate+glycine
Catalysed by AADAT
Reaction pageLeft to rightBalanced
Rhea RHEA:69112CC BY 4.0Reference data
2-oxoadipate+L-kynurenineL-2-aminoadipate+kynurenate+water
Catalysed by AADAT
Reaction pageLeft to rightBalanced
Rhea RHEA:70047CC BY 4.0Reference data

Show the remaining 3

Other names

1 name

Resolves to: L-2-aminoadipate

Systematic name: (2S)-2-azaniumylhexanedioate