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CDP-ethanolamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

192 compounds within 3 steps: 8 in 1, 43 in 2, 141 in 3

Does it reach a compound?

Two steps

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamineReach from here →
1. CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
2. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)
Catalysed by CEPT1, PEMT

Three steps

(S)-carnitineReach from here →
Catalysed by CEPT1, PLA2G2A, PLB1, PLA2G2E and 1 moreendoplasmic reticulum, cytosolOne of 2 routes
CHEBI:1146900Reach from here →

Page 2 of 4

Catalysed by SELENOI, CEPT1, PIGF, PIGG and 5 morecytosol, endoplasmic reticulumOne of 2 routes

AReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Catalysed by CEPT1, PLA2G4E, PTGS2One of 3 routes

N-(9Z-octadecenoyl)-L-phenylalanineReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoate + H(+)
L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O

Catalysed by CEPT1, PLA2G2A, PLB1, PLA2G2E and 2 more

N-(9Z-octadecenoyl)-L-leucineReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoate + H(+)
N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

Catalysed by CEPT1, PLA2G2A, PLB1, PLA2G2E and 2 more

a 3-(acyloxy)acyl derivative of bacterial toxinReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
a 3-(acyloxy)acyl derivative of bacterial toxin + H2O = a 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)

Catalysed by SELENOI, CEPT1, DDHD1, AOAH

2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Catalysed by CEPT1, PLA2G4E, PTGS2

2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Catalysed by CEPT1, PLA2G4E, PTGS2

2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Catalysed by CEPT1, PLA2G4E, PTGS2

2-(prostaglandin G2)-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + 2 O2 = 2-(prostaglandin G2)-sn-glycero-3-phosphocholine

Catalysed by CEPT1, PLA2G4E, PTGS2

sn-glycero-3-phosphoethanolamineReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)

Catalysed by SELENOI, CEPT1, PLA2G15, ASPGOne of 6 routes

a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)

Catalysed by SELENOI, CEPT1, PIGN, PIGB

cholineReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
Phosphatidylethanolamine N-Methyltransferase
phosphatidylserine synthase (PC-LD pool)

Catalysed by SELENOI, CEPT1, PEMT, PTDSS1cytosol, mitochondrial matrixOne of 8 routes

oleoyl-CoAReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoate + H(+)
long-chain-fatty-acid-CoA ligase (oleate)

Catalysed by CEPT1, PLA2G2A, PLB1, PLA2G2E and 9 morecytosolOne of 3 routes

hexadecanoic acidReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

a sterolReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine + H(+)
a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine

Catalysed by SELENOI, CEPT1, PLAAT5, PLAAT2 and 1 more

CHEBI:16132Reach from here →

CDP-ethanolamine + H2O = phosphoethanolamine + CMP + 2 H(+)
phosphoethanolamine + H2O = acetaldehyde + NH4(+) + phosphate
deoxyribose-phosphate aldolase

Catalysed by ADPRM, ETNPPL, DERAcytosol

sn-glycerol 3-phosphocholineReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine = sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine

Catalysed by SELENOI, CEPT1, PLA2G15, ASPGOne of 18 routes

a cholesterol esterReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
Phosphatidylethanolamine N-Methyltransferase
Phosphatidylcholine:sterol O-acyltransferase

Catalysed by SELENOI, CEPT1, PEMT, LCATcytosol, mitochondrial matrixOne of 2 routes

linoleic acidReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

a 2-acylglycerolReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)

Catalysed by SELENOI, CEPT1, PIGF, PIGG and 3 morecytosol, endoplasmic reticulum

a monoacylglycerolReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
1,2-diacyl-sn-glycerol acylhydrolase

Catalysed by SELENOI, CEPT1, PIGF, PIGG and 15 morecytosol, endoplasmic reticulum, extracellular spaceOne of 9 routes

1-O-acyl-sn-glycero-3-phosphocholine(1+)Reach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
Phosphatidylethanolamine N-Methyltransferase
phosphatidylcholine 2-acylhydrolase

Catalysed by SELENOI, CEPT1, PEMT, PLA2G10 and 17 morecytosol, mitochondrial matrix, endoplasmic reticulumOne of 8 routes

O-phosphoethanolamineReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
ATP:ethanolamine O-phosphotransferase

Catalysed by SELENOI, CEPT1, PTDSS2, CHKA and 3 morecytosolOne of 2 routes

hexadecanalReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)
hexadecanoate + NADH + 2 H(+) = hexadecanal + NAD(+) + H2O

Catalysed by CEPT1, DDHD2, ALDH3B1, ALDH3B2 and 1 more

all-trans-retinyl hexadecanoateReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)
all-trans-retinyl hexadecanoate + H2O = 11-cis-retinol + hexadecanoate + H(+)

Catalysed by CEPT1, DDHD2, RPE65

a sphingomyelinReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
Phosphatidylethanolamine N-Methyltransferase
ceramide:phosphatidylcholine cholinephosphotransferase

Catalysed by SELENOI, CEPT1, PEMT, SGMS1 and 1 morecytosol, mitochondrial matrix, Golgi apparatusOne of 4 routes

a triacylglycerolReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase

Catalysed by SELENOI, CEPT1, PIGF, PIGG and 5 morecytosol, endoplasmic reticulum

dodecanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)
a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by SELENOI, CEPT1, DDHD1, LPGAT1

S-hexadecanoyl-N-acetylcysteamineReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)
S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)

Catalysed by CEPT1, DDHD2, PPT1, PPT2

S-hexadecanoyl-N-acetylcysteine methyl esterReach from here →

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)
S-hexadecanoyl-N-acetylcysteine methyl ester + H2O = N-acetylcysteine methyl ester + hexadecanoate + H(+)

Catalysed by CEPT1, DDHD2, PPT1

docosanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

octadecanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase
fatty acylamide amidohydrolase

Catalysed by SELENOI, CEPT1, PTDSS2, FAAHcytosolOne of 2 routes

alpha-linolenic acidReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

elaidic acidReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

all-cis-docosa-4,7,10,13,16,19-hexaenoic acidReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

Catalysed by CEPT1, PLAAT5, PLAAT2, TAFAZZIN

phosphocholineReach from here →

CDP-ethanolamine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine + H(+)
a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycerol + phosphocholine + H(+)

Catalysed by SELENOI, CEPT1, PLAAT5, PLAAT2 and 1 moreOne of 2 routes

acetateReach from here →

CDP-ethanolamine + H2O = phosphoethanolamine + CMP + 2 H(+)
phosphoethanolamine + H2O = acetaldehyde + NH4(+) + phosphate
Acetaldehyde:NAD+ oxidoreductase

Catalysed by ADPRM, ETNPPL, ALDH3A1, ALDH3B1 and 2 morecytosolOne of 4 routes

tetradecanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

a 1-O-alkyl-sn-glycero-3-phosphocholineReach from here →

CDP-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)
a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine

Catalysed by CEPT1, PLAAT5, PLAAT2, LCAT

hexacosanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

tetracosanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

an N-acylsphinganineReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
N-acylsphingosine amidohydrolase

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 21 morecytosolOne of 2 routes

an N-acyl-(4R)-4-hydroxysphinganineReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
M4B Phosphoethanolaminyl Transferase, Endoplasmic Reticulum
an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

Catalysed by SELENOI, CEPT1, PIGF, PIGG and 2 morecytosol, endoplasmic reticulum

eicosanoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes

(9Z)-hexadecenoateReach from here →

CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase
phosphatidylethanolamine 2-acylhydrolase
(10Z)-heptadecenoic acid formation

Catalysed by SELENOI, CEPT1, PLA2G10, PLA2G6 and 16 morecytosol, extracellular spaceOne of 12 routes