CMP-N-acetyl-beta-neuraminate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

200 compounds within 3 steps: 51 in 1, 18 in 2, 131 in 3

Three steps

3-hydroxyisovaleryl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1Bcytosol
CHEBI:63544Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (adrenic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
hexacosanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
tetracosanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 9 routes
(2E)-octadecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Carnitine O-Palmitoyltransferase
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosolOne of 3 routes
an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineReach from here →
1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
2. Acylneuraminyl hydrolase
3. 3'-Phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase
Catalysed by ST3GAL5, NEU4, NEU1, NEU3 and 2 morelysosome
dodecanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Activation of dodecanedioic acid
Catalysed by ST8SIA1, SLC33A1cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Production of Sebacoylcarnitine
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Production of Suberylcarnitine
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by ST8SIA1, SLC33A1cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by ST8SIA1, SLC33A1, CRAT, CROTcytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by ST8SIA1, SLC33A1, ACAA1, HSD17B4 and 2 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Production of Hexadecanedioylcarnitine
Catalysed by ST8SIA1, SLC33A1, CPT1A, CPT1C and 1 morecytosolOne of 2 routes
a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →
1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
2. a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
3. a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)
Catalysed by ST3GAL6, NEU2, FUT5cytosol
pristanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. fatty-acid-CoA ligase
Catalysed by ST8SIA1, SLC33A1, SLC27A2cytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by ST8SIA1, SLC33A1, ACSM4, ACSM1 and 4 morecytosolOne of 3 routes
beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
2. exo-alpha-sialidase (GM3)
3. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
Catalysed by ST3GAL5, NEU4, NEU1, NEU3 and 2 morecytosol
a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramideReach from here →
1. a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 + CMP + H(+)
2. a ganglioside GD3 + H2O = a ganglioside GM3 + N-acetylneuraminate
3. a ganglioside GM3 + H2O = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetylneuraminate
Catalysed by ST8SIA3, ST8SIA6, NEU4, NEU3 and 1 more
a ganglioside GM2Reach from here →
1. a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 + CMP + H(+)
2. a ganglioside GD3 + H2O = a ganglioside GM3 + N-acetylneuraminate
3. a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + UDP + H(+)
Catalysed by ST8SIA3, ST8SIA6, NEU4, NEU3 and 2 more
(5Z)-tetradecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by ST8SIA1, SLC33A1, ACADM, ECHS1 and 2 morecytosol, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by ST8SIA1, SLC33A1, HADHA, ACAA2 and 1 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 8 routes
a ganglioside GA1Reach from here →
1. a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)
2. a ganglioside GD1a + H2O = a ganglioside GM1 + N-acetylneuraminate
3. a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate
Catalysed by ST3GAL1, ST3GAL2, NEU4, NEU3 and 1 more
tricosanoyl-CoAReach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
2. solute carrier (acetyl-CoA)
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by ST8SIA1, SLC33A1, SLC27A2, ACSL4 and 6 morecytosolOne of 4 routes
a ganglioside Fuc-GM1Reach from here →
1. a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)
2. a ganglioside GD1a + H2O = a ganglioside GM1 + N-acetylneuraminate
3. a ganglioside GM1 + GDP-beta-L-fucose = a ganglioside Fuc-GM1 + GDP + H(+)
Catalysed by ST3GAL1, ST3GAL2, NEU4, NEU3 and 3 more
a ganglioside Fuc-GD1bReach from here →
1. a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1b + CMP + H(+)
2. a ganglioside GT1b + H2O = a ganglioside GD1b + N-acetylneuraminate
3. a ganglioside GD1b + GDP-beta-L-fucose = a ganglioside Fuc-GD1b + GDP + H(+)
Catalysed by ST3GAL1, ST3GAL2, NEU3, NEU2 and 1 more