What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- CPT1AProteinUNIPROT:P50416substrate ofInferred only28 paths28 endpoints
- HSD17B4ProteinUNIPROT:P51659substrate ofInferred only27 paths27 endpoints
- ACAA1ProteinUNIPROT:P09110substrate ofInferred only24 paths24 endpoints
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only21 paths21 endpoints
- ACOX1ProteinUNIPROT:Q15067substrate ofInferred only15 paths15 endpoints
- CPT1BProteinUNIPROT:Q92523substrate ofInferred only8 paths8 endpoints
- CPT1CProteinUNIPROT:Q8TCG5substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: hexadecanedioyl-CoA · Sources: Human-GEM
- hexadecanedioyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR05331Inferred only
- hexadecanedioyl-CoA is a substrate of ACOX1ProteinHuman-GEM MAR05331Inferred only
- hexadecanedioyl-CoA is a substrate of CPT1AProteinHuman-GEM MAR04624Inferred only
- hexadecanedioyl-CoA is a substrate of CPT1BProteinHuman-GEM MAR04624Inferred only
- hexadecanedioyl-CoA is a substrate of CPT1CProteinHuman-GEM MAR04624Inferred only
- hexadecanedioyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR05331Inferred only
- hexadecanedioyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR05331Inferred only
Reactions
9 reactions
(S)-carnitine+hexadecanedioyl-CoACHEBI:1146900+MAM03493c
Catalysed by CPT1A or CPT1C or CPT1B
Reaction pageReversibleBalancedEC 2.3.1.21GO:0005829
Human-GEM MAR04624CC BY 4.0Reference data
CHEBI:1146900+FAD+water+NAD(+)+hexadecanedioyl-CoACHEBI:15351+FADH2+proton+NADH(2-)+tetradecanedioyl-CoA
Catalysed by ACAA1 & HSD17B4 & EHHADH & ACOX1
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05331CC BY 4.0Reference data
ATP+CHEBI:1146900+hexadecanedioateAMP+diphosphate(3-)+hexadecanedioyl-CoA
Catalysed by ACSL5
Reaction pageLeft to rightBalancedEC 6.2.1.3GO:0005783
Human-GEM MAR05334CC BY 4.0Reference data
hexadecanedioyl-CoAhexadecanedioyl-CoA
Transported by DBI
Reaction pageReversibleBalancedGO:0005783, GO:0005829
Human-GEM MAR06499CC BY 4.0Reference data
hexadecanedioyl-CoAhexadecanedioyl-CoA
Transported by DBI
Reaction pageLeft to rightBalancedGO:0005783, GO:0005777
Human-GEM MAR06502CC BY 4.0Reference data
hexadecanedioyl-CoA+dioxygenCHEBI:77075+hydrogen peroxide
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:40275CC BY 4.0Reference data
hexadecanedioyl-CoA+(R)-carnitineCHEBI:77087+coenzyme A(4-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:40283CC BY 4.0Reference data
hexadecanedioate+ATP(4-)+coenzyme A(4-)hexadecanedioyl-CoA+AMP+diphosphate(3-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:40295CC BY 4.0Reference data
hexadecanedioyl-CoA+waterhexadecanedioate+coenzyme A(4-)+hydron
Catalysed by ABCD3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:67696CC BY 4.0Reference data