Compound
pristanoyl-CoA
A multi-methyl-branched fatty acyl-CoA(4-) oxanion arising from deprotonation of the phosphate and diphosphate OH groups of pristanoyl-CoA; major species at pH 7.3.
Definition from ChEBI (CHEBI:77250), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C40H68N7O17P3S
- Mass
- 1044.005 g/mol
- Charge
- -4
- InChIKey
- XYJPSQPVCBNZHT-TUKYSRJDSA-J
- SMILES
- CC(C)CCCC(C)CCCC(C)CCCC(C)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- ABCD3ProteinUNIPROT:P28288transported byInferred only87 paths82 endpoints
- HSD17B4ProteinUNIPROT:P51659substrate ofInferred only54 paths27 endpoints
- ACAA1ProteinUNIPROT:P09110substrate ofInferred only48 paths24 endpoints
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only42 paths21 endpoints
- ACOX3ProteinUNIPROT:O15254substrate ofInferred only22 paths11 endpoints
- ACOT2ProteinUNIPROT:P49753substrate ofInferred only22 paths22 endpoints
What the reference databases state
Statements
10 statements
10 statements · 1 reference database · Subject: pristanoyl-CoA · Sources: Human-GEM
- pristanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR05184Inferred only
- pristanoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR01600Inferred only
- pristanoyl-CoA is a substrate of ACOT2ProteinHuman-GEM MAR01674Inferred only
- pristanoyl-CoA is a substrate of ACOX3ProteinHuman-GEM MAR01600Inferred only
- pristanoyl-CoA is a substrate of ACOX3ProteinHuman-GEM MAR05184Inferred only
- pristanoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR05184Inferred only
- pristanoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR01600Inferred only
- pristanoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR01600Inferred only
- pristanoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR05184Inferred only
- pristanoyl-CoA is transported by ABCD3ProteinHuman-GEM MAR06775Inferred only
Reactions
9 reactions
ATP+CHEBI:1146900+2,6,10,14-tetramethylpentadecanoateAMP+diphosphate(3-)+pristanoyl-CoA
Catalysed by SLC27A2
Reaction pageLeft to rightBalancedEC 6.2.1.3GO:0005829
Human-GEM MAR00739CC BY 4.0Reference data
3CHEBI:1146900+2FAD+3water+3NAD(+)+pristanoyl-CoACHEBI:15351+2FADH2+5proton+3NADH(2-)+2propionyl-CoA+4,8-dimethylnonanoyl-CoA
Catalysed by ACOX3 & ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightUnbalancedEC 3.1.4.17GO:0005777
Human-GEM MAR01600CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005777, GO:0005829
Human-GEM MAR01647CC BY 4.0Reference data
water+pristanoyl-CoACHEBI:1146900+proton+2,6,10,14-tetramethylpentadecanoate
Catalysed by ACOT2
Reaction pageLeft to rightBalancedEC 3.1.2.2GO:0005777
Human-GEM MAR01674CC BY 4.0Reference data
ATP+CHEBI:1146900+2,6,10,14-tetramethylpentadecanoateAMP+diphosphate(3-)+pristanoyl-CoA
Catalysed by SLC27A2
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05183CC BY 4.0Reference data
CHEBI:1146900+FAD+water+NAD(+)+pristanoyl-CoA4,8,12-trimethyltridecanoyl-CoA+FADH2+proton+NADH(2-)+propionyl-CoA
Catalysed by ACOX3 & ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05184CC BY 4.0Reference data
ATP+water+pristanoyl-CoAADP+proton+phosphate(3-)+pristanoyl-CoA
Transported by ABCD3
Reaction pageLeft to rightBalancedGO:0005829, GO:0005777
Human-GEM MAR06775CC BY 4.0Reference data
pristanoyl-CoA+water2,6,10,14-tetramethylpentadecanoate+coenzyme A(4-)+hydron
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:40415CC BY 4.0Reference data
2,6,10,14-tetramethylpentadecanoate+ATP(4-)+coenzyme A(4-)pristanoyl-CoA+AMP+diphosphate(3-)
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47264CC BY 4.0Reference data
Where it reaches
10 systems, 25 regions, 78 tissues, 78 transporter routes — routes, not measurements: transporters known to carry pristanoyl-CoA are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: pristanoyl-CoA
- Also called
- pristanoyl-coenzyme A(4-)pristanoyl-coenzyme A(4−)