What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- CPT1AProteinUNIPROT:P50416substrate ofInferred only28 paths28 endpoints
- HSD17B4ProteinUNIPROT:P51659substrate ofInferred only27 paths27 endpoints
- ACAA1ProteinUNIPROT:P09110substrate ofInferred only24 paths24 endpoints
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only21 paths21 endpoints
- ACOT8ProteinUNIPROT:O14734substrate ofInferred only16 paths16 endpoints
- ACOX1ProteinUNIPROT:Q15067substrate ofInferred only15 paths15 endpoints
- CPT1BProteinUNIPROT:Q92523substrate ofInferred only8 paths8 endpoints
- CROTProteinUNIPROT:Q9UKG9substrate ofInferred only7 paths7 endpoints
- CPT1CProteinUNIPROT:Q8TCG5substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: decanedioyl-CoA · Sources: Human-GEM
- decanedioyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR05026Inferred only
- decanedioyl-CoA is a substrate of ACOT8ProteinHuman-GEM MAR06810Inferred only
- decanedioyl-CoA is a substrate of ACOX1ProteinHuman-GEM MAR05026Inferred only
- decanedioyl-CoA is a substrate of CPT1AProteinHuman-GEM MAR04491Inferred only
- decanedioyl-CoA is a substrate of CPT1BProteinHuman-GEM MAR04491Inferred only
- decanedioyl-CoA is a substrate of CPT1CProteinHuman-GEM MAR04491Inferred only
- decanedioyl-CoA is a substrate of CROTProteinHuman-GEM MAR06809Inferred only
- decanedioyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR05026Inferred only
- decanedioyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR05026Inferred only
Reactions
12 reactions
(S)-carnitine+decanedioyl-CoACHEBI:1146900+MAM03489c
Catalysed by CPT1A or CPT1C or CPT1B
Reaction pageReversibleBalancedEC 2.3.1.21GO:0005829
Human-GEM MAR04491CC BY 4.0Reference data
CHEBI:1146900+FAD+water+NAD(+)+decanedioyl-CoACHEBI:15351+FADH2+proton+NADH(2-)+octanedioyl-CoA
Catalysed by ACAA1 & HSD17B4 & EHHADH & ACOX1
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05026CC BY 4.0Reference data
CHEBI:1146900+FAD+water+NAD(+)+dodecanedioyl-CoACHEBI:15351+FADH2+proton+NADH(2-)+decanedioyl-CoA
Catalysed by ACAA1 & HSD17B4 & EHHADH & ACOX1
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05100CC BY 4.0Reference data
ATP+CHEBI:1146900+MAM03923cAMP+diphosphate(3-)+decanedioyl-CoA
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR06804CC BY 4.0Reference data
(S)-carnitine+decanedioyl-CoACHEBI:1146900+MAM03489x
Catalysed by CROT
Reaction pageReversibleBalancedEC 2.3.1.137GO:0005777
Human-GEM MAR06809CC BY 4.0Reference data
water+decanedioyl-CoACHEBI:1146900+proton+MAM03923x
Catalysed by ACOT8
Reaction pageLeft to rightBalancedEC 3.1.2.-GO:0005777
Human-GEM MAR06810CC BY 4.0Reference data
FAD+water+decanedioyl-CoAFADH2+MAM03259x
Catalysed by EHHADH & ACOX1 or ECH1 & ACOX1
Reaction pageLeft to rightBalancedEC 1.3.3.6, 4.2.1.17GO:0005777
Human-GEM MAR11534CC BY 4.0Reference data
CHEBI:76346+coenzyme A(4-)decanedioyl-CoA+acetyl-CoA
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:39083CC BY 4.0Reference data
decanedioyl-CoA+dioxygenCHEBI:76347+hydrogen peroxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:39087CC BY 4.0Reference data
CHEBI:76283+ATP(4-)+coenzyme A(4-)decanedioyl-CoA+AMP+diphosphate(3-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:40287CC BY 4.0Reference data
decanedioyl-CoA+ACHEBI:76347+AH2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:40307CC BY 4.0Reference data
decanedioyl-CoA+waterCHEBI:76283+coenzyme A(4-)+hydron
Catalysed by ACOT8
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:40591CC BY 4.0Reference data