Compound

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al

CHEBI:48940ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

20 statements

20 statements · 1 reference database · Subject: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al · Sources: Human-GEM

Order

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-alCompoundHuman-GEM MAR03214Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-alCompoundHuman-GEM MAR03815Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-alCompoundHuman-GEM MAR03817Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR01611Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-alCompoundHuman-GEM MAR03821Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR01613Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR01614Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR03210Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR03214Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR03815Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oateCompoundHuman-GEM MAR03821Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate is converted to (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-alCompoundHuman-GEM MAR03210Inferred only

Show the remaining 8

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by ALDH3A1ProteinHuman-GEM MAR03821Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by ALDH3A1ProteinHuman-GEM MAR03815Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by ALDH3A2ProteinHuman-GEM MAR03821Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by ALDH9A1ProteinHuman-GEM MAR03815Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by CYP27A1ProteinHuman-GEM MAR03214Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by CYP27A1ProteinHuman-GEM MAR01611Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by CYP27A1ProteinHuman-GEM MAR01613Inferred only
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al is metabolised by CYP27A1ProteinHuman-GEM MAR01614Inferred only

Reactions

18 reactions

MAM01090c+NAD(+)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADH(2-)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005829
Human-GEM MAR01608CC BY 4.0Reference data
MAM01090m+NAD(+)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADH(2-)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01609CC BY 4.0Reference data
MAM01090m+NADP(3-)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADPH(4-)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01610CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+water+NAD(+)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+2proton+NADH(2-)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005829
Human-GEM MAR01611CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+NADH(2-)+dioxygen(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+water+NAD(+)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01613CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+NADPH(4-)+dioxygen(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+water+NADP(3-)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01614CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADH(2-)MAM01092c+NAD(+)
Catalysed by CYP27A1
Reaction pageReversibleBalancedEC 1.14.15.15GO:0005829
Human-GEM MAR01803CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADH(2-)MAM01092m+NAD(+)
Catalysed by CYP27A1
Reaction pageReversibleBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01806CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+waterMAM01091m
Catalysed by CYP27A1
Reaction pageReversibleBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR01807CC BY 4.0Reference data
MAM01090m+NAD(+)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+proton+NADH(2-)
Catalysed by CYP27A1
Reaction pageReversibleBalancedEC 1.14.14.55GO:0005759
Human-GEM MAR03209CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+water+NADP(3-)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+2proton+NADPH(4-)
Reaction pageReversibleBalancedGO:0005829
Human-GEM MAR03210CC BY 4.0Reference data
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al+water+NADP(3-)(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate+2proton+NADPH(4-)
Catalysed by CYP27A1
Reaction pageReversibleBalancedEC 1.14.15.15GO:0005759
Human-GEM MAR03214CC BY 4.0Reference data

Show the remaining 6