Compound
4-(trimethylamino)butanoate
An amino-acid betaine γ-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups.
Definition from ChEBI (CHEBI:16244), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C7H15NO2
- Mass
- 145.202 g/mol
- Charge
- 0
- InChIKey
- JHPNVNIEXXLNTR-UHFFFAOYSA-N
- SMILES
- C[N+](C)(C)CCCC(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Chemical structure
- 4-(trimethylamino)butanoate has the functional parent 4-aminobutanoateCompoundChEBI CHEBI:16244Inferred only
Statements
6 statements
6 statements · 2 reference databases · Subject: 4-(trimethylamino)butanoate · Sources: Human-GEM, Rhea
- 4-(trimethylamino)butanoate is converted to (S)-carnitineCompoundHuman-GEM MAR06982Inferred only
- 4-(trimethylamino)butanoate is converted to 4-(trimethylamino)butanalCompoundRhea RHEA:17985Inferred only
- 4-(trimethylamino)butanal is converted to 4-(trimethylamino)butanoateCompoundRhea RHEA:17985Inferred only
- 4-(trimethylamino)butanal is converted to 4-(trimethylamino)butanoateCompoundHuman-GEM MAR06981Inferred only
- 4-(trimethylamino)butanoate is metabolised by ALDH9A1ProteinRhea RHEA:17985Inferred only
- 4-(trimethylamino)butanoate is a substrate of BBOX1ProteinHuman-GEM MAR06982Inferred only
Reactions
12 reactions
4-(trimethylamino)butanal+water+NAD(+)4-(trimethylamino)butanoate+2proton+NADH(2-)
Catalysed by ALDH9A1
Reaction pageLeft to rightBalancedEC 1.2.1.47GO:0005829
Human-GEM MAR06981CC BY 4.0Reference data
2-oxoglutarate(2-)+4-(trimethylamino)butanoate+dioxygencarbon dioxide+(S)-carnitine+succinate(2-)
Catalysed by BBOX1
Reaction pageLeft to rightBalancedEC 1.14.11.1GO:0005829
Human-GEM MAR06982CC BY 4.0Reference data
4-(trimethylamino)butanoate+sodium(1+)4-(trimethylamino)butanoate+sodium(1+)
Reaction pageReversibleBalancedEC 3.1.1.4GO:0005829, GO:0005615
Human-GEM MAR09979CC BY 4.0Reference data
4-(trimethylamino)butanoate+proton4-(trimethylamino)butanoate+proton
Reaction pageReversibleBalancedEC 3.1.1.4GO:0005829, GO:0005615
Human-GEM MAR09980CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR10191CC BY 4.0Reference data
4-(trimethylamino)butanal+NAD(1-)+water4-(trimethylamino)butanoate+NADH(2-)+2hydron
Catalysed by ALDH9A1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:17985CC BY 4.0Reference data
4-(trimethylamino)butanoate+2-oxoglutarate(2-)+dioxygenCHEBI:17126+succinate(2-)+carbon dioxide
Catalysed by BBOX1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24028CC BY 4.0Reference data
CHEBI:61513+(R)-carnitineCHEBI:60932+4-(trimethylamino)butanoate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:28418CC BY 4.0Reference data
4-(trimethylamino)butanoate+(R)-carnitine4-(trimethylamino)butanoate+(R)-carnitine
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:29427CC BY 4.0Reference data
4-(trimethylamino)butanoate4-(trimethylamino)butanoate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:32835CC BY 4.0Reference data
4-(trimethylamino)butanoate+ATP(4-)+coenzyme A(4-)CHEBI:61513+AMP+diphosphate(3-)
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:55960CC BY 4.0Reference data
4-(trimethylamino)butanoate+NADH(2-)+dioxygen+hydronsuccinate semialdehyde+CHEBI:58389+NAD(1-)+water
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:58488CC BY 4.0Reference data
On the label
Labelled products
4 products
Source: NIH DSLD · Ingredient: 4-(trimethylamino)butanoate · 4 products · Declared amount per serving: 12.5–25 mg (4 products)
4 labels state an amount0 do not
- InnovaPharmNovaLean Grape HeadzGamma-Butyrobetaine Ethyl Ester Chloride25 mgper 7.4 Gram(s)DSLD:299177
- Morphogen NutritionMorphoburnGamma-Butyrobetaine Ethyl Ester12.5 mgper 2 Capsule(s)DSLD:212754
- Nutricost PerformancePRE-SF Pink Lemonade15 mgper 19 Gram(s)DSLD:308246
- VMI SportsWhite Heat Ultra Burn25 mgper 2 Capsule(s)DSLD:257733
Label record: NIH Office of Dietary Supplements · CC0
Other names
9 names
Resolves to: 4-(trimethylamino)butanoate
- Also called
- 3-Dehydroxycarnitine4-(N-trimethylamino)butyrate4-butyrobetaineActininebutyrobetainedeoxycarnitinegamma-butyrobetaineγ-butyrobetaine
- Systematic name
- 4-(trimethylammonio)butanoate