What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- ALDH2ProteinUNIPROT:P05091metabolized byInferred only64 paths32 endpoints
- ALDH7A1ProteinUNIPROT:P49419metabolized byInferred only26 paths13 endpoints
- ALDH1B1ProteinUNIPROT:P30837metabolized byInferred only22 paths11 endpoints
- ALDH3A2ProteinUNIPROT:P51648metabolized byInferred only14 paths14 endpoints
- ALDH9A1ProteinUNIPROT:P49189metabolized byInferred only7 paths7 endpoints
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: indole-3-acetaldehyde · Sources: Human-GEM
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is converted to (indol-3-yl)acetateCompoundHuman-GEM MAR08563Inferred only
- tryptamine is converted to indole-3-acetaldehydeCompoundHuman-GEM MAR06713Inferred only
- indole-3-acetaldehyde is metabolised by ALDH1B1ProteinHuman-GEM MAR08563Inferred only
- indole-3-acetaldehyde is metabolised by ALDH1B1ProteinHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is metabolised by ALDH2ProteinHuman-GEM MAR08563Inferred only
- indole-3-acetaldehyde is metabolised by ALDH2ProteinHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is metabolised by ALDH3A2ProteinHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is metabolised by ALDH7A1ProteinHuman-GEM MAR06714Inferred only
- indole-3-acetaldehyde is metabolised by ALDH7A1ProteinHuman-GEM MAR08563Inferred only
- indole-3-acetaldehyde is metabolised by ALDH9A1ProteinHuman-GEM MAR06714Inferred only
Reactions
10 reactions
water+dioxygen+tryptamineproton+hydrogen peroxide+indole-3-acetaldehyde+ammonium
Catalysed by AOC1 or MAOB or MAOA
Reaction pageLeft to rightBalancedEC 1.4.3.4, 1.4.3.22GO:0005829
Human-GEM MAR06713CC BY 4.0Reference data
water+indole-3-acetaldehyde+NAD(+)2proton+(indol-3-yl)acetate+NADH(2-)
Catalysed by ALDH3A2 or ALDH2 or ALDH1B1 or ALDH9A1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.3GO:0005829
Human-GEM MAR06714CC BY 4.0Reference data
indole-3-acetaldehydeindole-3-acetaldehyde
Reaction pageReversibleBalancedGO:0005829, GO:0005759
Human-GEM MAR08562CC BY 4.0Reference data
water+indole-3-acetaldehyde+NAD(+)2proton+(indol-3-yl)acetate+NADH(2-)
Catalysed by ALDH2 or ALDH1B1 or ALDH7A1
Reaction pageLeft to rightBalancedEC 1.2.1.4, 1.2.1.5GO:0005759
Human-GEM MAR08563CC BY 4.0Reference data
CHEBI:17890+NAD(1-)indole-3-acetaldehyde+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:14873CC BY 4.0Reference data
indole-3-acetaldehyde+dioxygen+water(indol-3-yl)acetate+hydrogen peroxide+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16277CC BY 4.0Reference data
CHEBI:17890+NADP(3-)indole-3-acetaldehyde+NADPH(4-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:17037CC BY 4.0Reference data
indole-3-pyruvate+hydronindole-3-acetaldehyde+carbon dioxide
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18017CC BY 4.0Reference data
indole-3-acetaldehyde+NAD(1-)+water(indol-3-yl)acetate+NADH(2-)+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:30867CC BY 4.0Reference data
tryptamine+dioxygen+waterindole-3-acetaldehyde+hydrogen peroxide+ammonium
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:59416CC BY 4.0Reference data