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Reach

an N(2)-acyl-L-glutamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

611 compounds within 3 steps: 2 in 1, 108 in 2, 501 in 3

Does it reach a compound?

Two steps

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
a 1,3-diacyl-sn-glycerolReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by GLYATL1B, GLYATL1, MOGAT1One of 2 routes
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT2, LPCAT1
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by GLYATL1B, GLYATL1, LPCAT4
(5Z)-tetradecenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
(7Z)-hexadecenoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
tricosanoyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. acyl-CoA pool formation and breakdown
Catalysed by GLYATL1B, GLYATL1cytosol
a 3-oxoacyl-CoAReach from here →
1. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Catalysed by GLYATL1B, GLYATL1, ACAA1, SCP2 and 2 more

Three steps

beta-carbolineReach from here →
Catalysed by GLYATL1B, GLYATL1, SLC7A5extracellular space, cytosol
(S)-carnitineReach from here →
Catalysed by GLYATL1B and 5 more

Page 3 of 13

, GLYATL1

, GPAT3

, GPAT2

mitochondrial matrix, cytosol

One of 245 routes

N(omega)-methyl-L-arginineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
L-Glutamine:pyruvate aminotransferase
N(omega)-methyl-L-arginine + pyruvate = 5-(3-methylguanidino)-2-oxopentanoate + L-alanine

Catalysed by GLYATL1B, GLYATL1, KYAT1, AGXT2cytosolOne of 4 routes

3-methyl-2-oxobutanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and valine (cytosol to extracellular)
L-Valine:2-oxoglutarate aminotransferase

Catalysed by GLYATL1B, GLYATL1, SLC7A5, BCAT2extracellular space, cytosol, mitochondrial matrixOne of 3 routes

AReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of cysteine and glutamine (cytosol to extracellular)
Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

Catalysed by GLYATL1B, GLYATL1, SLC3A2, SLC7A5 and 2 moreextracellular space, cytosol

S-dodecanoyl-4'-phosphopantetheineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
dodecanoyl-CoA + H2O = S-dodecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by GLYATL1B, GLYATL1, NUDT19, NUDT7cytosol

tetradecanoyl-4'-phosphopantetheineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
tetradecanoyl-CoA + H2O = tetradecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by GLYATL1B, GLYATL1, NUDT19, NUDT7cytosol

glycoursodeoxycholateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
glycine to glycoursodeoxycholate conversion

Catalysed by GLYATL1B, GLYATL1, SLC7A5extracellular space, cytosolOne of 2 routes

N-(9Z-octadecenoyl)glycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
(9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, SLC7A5, GLYATL3 and 1 moreextracellular space, cytosol

N-(9Z-octadecenoyl)-L-phenylalanineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and phenylalanine (cytosol to extracellular)
L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O

Catalysed by GLYATL1B, GLYATL1, SLC7A5, PM20D1extracellular space, cytosol

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and phenylalanine (cytosol to extracellular)
(5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine + H2O

Catalysed by GLYATL1B, GLYATL1, SLC7A5, PM20D1extracellular space, cytosol

N-(9Z-octadecenoyl)-L-leucineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and leucine (cytosol to extracellular)
N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

Catalysed by GLYATL1B, GLYATL1, SLC7A5, PM20D1extracellular space, cytosol

N-octadecanoylglycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, GLYATL2cytosolOne of 2 routes

N-(9Z-hexadecenoyl)-glycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
(9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, GLYATL2cytosolOne of 2 routes

5-amino-1-(5-phospho-beta-D-ribosyl)imidazoleReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + L-glutamine + ATP + H2O = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + L-glutamate + ADP + phosphate + H(+)
2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + phosphate + H(+)

Catalysed by GLYATL1B, GLYATL1, PFAS, GART

2-hydroxyeicosanoyl-CoAReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
eicosanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyeicosanoyl-CoA + succinate + CO2

Catalysed by GLYATL1B, GLYATL1, PHYHcytosol

2-hydroxydodecanoyl-CoAReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
dodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxydodecanoyl-CoA + succinate + CO2

Catalysed by GLYATL1B, GLYATL1, PHYHcytosol

2-hydroxytetradecanoyl-CoAReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
tetradecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxytetradecanoyl-CoA + succinate + CO2

Catalysed by GLYATL1B, GLYATL1, PHYHcytosol

11-cis-retinyl tetradecanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA

Catalysed by GLYATL1B, GLYATL1, AWAT2cytosol

9-cis-retinyl tetradecanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA

Catalysed by GLYATL1B, GLYATL1, AWAT2cytosol

13-cis-retinyl tetradecanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
13-cis-retinol + tetradecanoyl-CoA = 13-cis-retinyl tetradecanoate + CoA

Catalysed by GLYATL1B, GLYATL1, AWAT2cytosol

all-trans-retinyl tetradecanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
all-trans-retinol + tetradecanoyl-CoA = all-trans-retinyl tetradecanoate + CoA

Catalysed by GLYATL1B, GLYATL1, AWAT2cytosol

tetradecyl tetradecanoateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
tetradecan-1-ol + tetradecanoyl-CoA = tetradecyl tetradecanoate + CoA

Catalysed by GLYATL1B, GLYATL1, AWAT2cytosol

1-(9Z-octadecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z-octadecenoyl)-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA

Catalysed by GLYATL1B, GLYATL1, AGPAT4cytosol

N-hexadecanoylglycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, SLC7A5, GLYATL3extracellular space, cytosol

N-dodecanoylglycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, GLYATL2cytosolOne of 2 routes

N-decanoylglycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, SLC7A5, GLYATL2extracellular space, cytosol

N-octanoylglycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, SLC7A5, GLYATL2extracellular space, cytosol

D-histidineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and ornithine (cytosol to extracellular)
D-histidine(in) + L-ornithine(out) + H(+)(in) = D-histidine(out) + L-ornithine(in) + H(+)(out)

Catalysed by GLYATL1B, GLYATL1, SLC7A6, SLC25A2extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

L-homoarginineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of arginine and glutamine (cytosol to extracellular)
L-homoarginine(in) + L-arginine(out) = L-homoarginine(out) + L-arginine(in)

Catalysed by GLYATL1B, GLYATL1, SLC7A6, SLC25A29extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

L-homocarnosineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and histidine (cytosol to extracellular)
Formation of homocarnosine

Catalysed by GLYATL1B, GLYATL1, SLC7A6, CARNS1extracellular space, cytosol

N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
phosphoribosyl pyrophosphate amidotransferase (glutamine)
5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)

Catalysed by GLYATL1B, GLYATL1, PPAT, GARTcytosolOne of 2 routes

L-cystine-bis-glycineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine

Catalysed by GLYATL1B, GLYATL1, SLC7A5, DPEP1 and 1 moreextracellular space, cytosol

a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by GLYATL1B, GLYATL1, LPCAT4, LPCAT3 and 3 more

a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-(alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by GLYATL1B, GLYATL1, LPCAT4, LPCAT3 and 3 more

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by GLYATL1B, GLYATL1, LPCAT4, LPCAT3 and 3 more

a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-6-[6-phosphoethanolamine-alpha-D-mannosyl-(1->2)-6-phosphoethanolamine-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a 1,2-diacyl-sn-glycerol

Catalysed by GLYATL1B, GLYATL1, LPCAT4, LPCAT3 and 3 more

an N-octadecanoyl-sphingoid baseReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
acyl-CoA pool formation and breakdown
a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1, CERS1cytosol

2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactoneReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
D-glucosamine 6-phosphate + NADP(+) = 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + 2 H(+)

Catalysed by GLYATL1B, GLYATL1, GFPT2, GFPT1 and 1 more

glycyldehydrophenylalanineReach from here →

an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
transport of glutamine and glycine (cytosol to extracellular)
glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine

Catalysed by GLYATL1B, GLYATL1, SLC7A5, DPEP1extracellular space, cytosol