hexadecanedioate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

110 compounds within 3 steps: 1 in 1, 2 in 2, 107 in 3

One step

hexadecanedioyl-CoAReach from here →
1. Fatty Acid Activation (C16Dc), Endoplasmatic Reticulum
Catalysed by ACSL5endoplasmic reticulum

Two steps

CHEBI:1146900Reach from here →
1. Fatty Acid Activation (C16Dc), Endoplasmatic Reticulum
2. Production of Hexadecanedioylcarnitine
Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosol
tetradecanedioyl-CoAReach from here →
1. Fatty Acid Activation (C16Dc), Endoplasmatic Reticulum
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by ACSL5, ACAA1, HSD17B4, EHHADH and 1 moreendoplasmic reticulum, peroxisome

Three steps

(S)-carnitineReach from here →
Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 244 routes
(7Z)-octadecenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B

endoplasmic reticulum, cytosol

One of 3 routes

CHEBI:15345Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosolOne of 2 routes

cholineReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol, nucleus

CHEBI:15380Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 2 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 2 routes

isobutyryl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 11 routes

CHEBI:15519Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, peroxisomeOne of 2 routes

palmitoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 11 routes

oleoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 11 routes

phenylacetyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 3 routes

propionyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosolOne of 43 routes

CHEBI:15650Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 32 moreendoplasmic reticulum, cytosolOne of 2 routes

CHEBI:15727Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol

CHEBI:15746Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 2 moreendoplasmic reticulum, cytosolOne of 2 routes

11-cis-retinolReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 5 moreendoplasmic reticulum, cytosol

oxaloacetateReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol

anilineReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 2 moreendoplasmic reticulum, cytosol

CHEBI:17312Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 2 routes

L-cysteineReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol, mitochondrial matrix

(7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrix

CHEBI:17927Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosol

(5Z)-dodecenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

(11Z)-docosenoyl-CoA(4-)Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 5 routes

(7Z)-tetradecenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 8 routes

(4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

(7Z,10Z)-hexadecadienoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrix

(4Z,7Z)-decadienoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

(5Z)-octenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

CHEBI:27540Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 6 moreendoplasmic reticulum, cytosolOne of 6 routes

elaidic acidReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 5 routes

CHEBI:28701Reach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, peroxisomeOne of 7 routes

taurineReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosolOne of 2 routes

glycineReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 3 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 10 routes

(R)-methylmalonyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol, mitochondrial matrixOne of 2 routes

(S)-methylmalonyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosol, mitochondrial matrix

3'-dephospho-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 1 moreendoplasmic reticulum, cytosol, lysosomeOne of 2 routes

(2E)-dodecenoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosol, mitochondrial matrixOne of 3 routes

4,8,12-trimethyltridecanoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 2 moreendoplasmic reticulum, cytosol, peroxisomeOne of 2 routes

(6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 7 routes

butanoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 6 moreendoplasmic reticulum, cytosolOne of 9 routes

dodecanoyl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1B and 7 moreendoplasmic reticulum, cytosolOne of 9 routes

glutaryl-CoAReach from here →

Catalysed by ACSL5, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 2 routes