3-oxooctadecanoyl-CoA

Three steps

• L,L-cystathionineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. N-acetylglutamate synthase (N-acetyl-L-cystathionine)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 4 moreperoxisome, cytosol, mitochondrial matrix

• (3Z)-dodecenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. acetyl-CoA C-acyltransferase (3-oxomyrist-5-enoyl-CoA)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 6 moreperoxisome, cytosol, mitochondrial matrixOne of 3 routes

• a 1,2-diacyl-sn-glycero-3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA

  Catalysed by ACAA1, MYO5B, AGPAT2, GPAT3 and 11 moreperoxisome, cytosol

• (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 5 moreperoxisome, cytosol, endoplasmic reticulumOne of 3 routes

• deoxycholoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 5 moreperoxisome, cytosolOne of 4 routes

• (2E)-tetradecenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Fatty Acid Beta Oxidation (C16->C14), Mitochondrial
  3. trans-tetradec-2-enoyl-CoA reductase

  Catalysed by ACAA1, MYO5B, HADHA, ACADVL and 2 moreperoxisome, mitochondrial matrixOne of 5 routes

• decanoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. medium-chain acyl-CoA ligase (decanoic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 9 moreperoxisome, cytosolOne of 8 routes

• a cardiolipinReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA = a cardiolipin + CoA

  Catalysed by ACAA1, MYO5B, HADHAperoxisome, cytosol

• (2E)-octenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Beta Oxidation of Long Chain Fatty Acid
  3. trans-oct-2-enoyl-CoA reductase

  Catalysed by ACAA1, MYO5B, ACADM, ACADS and 1 moreperoxisome, mitochondrial matrixOne of 5 routes

• 3-hydroxyisovaleryl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 5 moreperoxisome, cytosol

• an all-trans-retinyl esterReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA

  Catalysed by ACAA1, MYO5B, DGAT1, PNPLA4 and 2 moreperoxisome, cytosol

• CHEBI:63544Reach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (adrenic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 8 routes

• hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
  3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = hexadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)

  Catalysed by SCP2, HADHB, PRDX6, LPCAT3 and 3 moreOne of 2 routes

• a 1,2-diacyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA

  Catalysed by ACAA1, MYO5B, LPCAT4, LPCAT3 and 2 moreperoxisome, cytosol

• a triacyl-sn-glycerolReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA

  Catalysed by ACAA1, MYO5B, DGAT1, MOGAT2 and 4 moreperoxisome, cytosol

• a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. acyl-CoA pool formation and breakdown
  3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

  Catalysed by ACAA1, MYO5B, LCLAT1, LPCAT1 and 1 moreperoxisome, cytosol

• hexacosanoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (cerotic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 6 routes

• tetracosanoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (lignocerate)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 11 routes

• 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositolReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA

  Catalysed by ACAA1, MYO5B, LCLAT1peroxisome, cytosol

• docosanoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (behenic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 10 routes

• 3-oxoeicosasphinganineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. octadecanoyl-CoA + L-serine + H(+) = 3-oxoeicosasphinganine + CO2 + CoA

  Catalysed by ACAA1, MYO5B, SPTLC1, SPTLC2 and 1 moreperoxisome, cytosol

• 3-oxoeicosanoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. very-long-chain 3-oxoacyl-CoA synthase (malonyl-CoA)

  Catalysed by ACAA1, MYO5B, ELOVL7, ELOVL1 and 5 moreperoxisome, cytosolOne of 2 routes

• N-(octadecanoyl)-sphinganineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)

  Catalysed by ACAA1, MYO5B, CERS1, CERS6 and 4 moreperoxisome, cytosol

• N-(2-hydroxyhexadecanoyl)-sphinganineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. hexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexadecanoyl-CoA + succinate + CO2
  3. 2-hydroxyhexadecanoyl-CoA + sphinganine = N-(2-hydroxyhexadecanoyl)-sphinganine + CoA + H(+)

  Catalysed by SCP2, HADHB, PHYH, CERS5

• N-(tetradecanoyl)-sphinganineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Fatty Acid Beta Oxidation (C16->C14), Mitochondrial
  3. sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)

  Catalysed by ACAA1, MYO5B, HADHA, ACADVL and 3 moreperoxisome, mitochondrial matrix

• 3-oxohexadecasphinganineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Fatty Acid Beta Oxidation (C16->C14), Mitochondrial
  3. tetradecanoyl-CoA + L-serine + H(+) = 3-oxohexadecasphinganine + CO2 + CoA

  Catalysed by ACAA1, MYO5B, HADHA, ACADVL and 3 moreperoxisome, mitochondrial matrix

• (2E)-octadecenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. Carnitine O-Palmitoyltransferase

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 6 moreperoxisome, cytosolOne of 9 routes

• (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (stearidonic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 9 routes

• 1-tetradecanoyl-sn-glycerol 3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Fatty Acid Beta Oxidation (C16->C14), Mitochondrial
  3. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)

  Catalysed by ACAA1, MYO5B, HADHA, ACADVL and 5 moreperoxisome, mitochondrial matrix, cytosol

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA

  Catalysed by ACAA1, MYO5B, LCLAT1peroxisome, cytosol

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

  Catalysed by ACAA1, MYO5B, LCLAT1, LPGAT1peroxisome, cytosol

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by ACAA1, MYO5B, GPAT3, GPAT2 and 3 moreperoxisome, cytosolOne of 2 routes

• 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA

  Catalysed by ACAA1, MYO5B, GPAT3, GPAT2 and 3 moreperoxisome, cytosolOne of 2 routes

• 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA

  Catalysed by ACAA1, MYO5B, GPAT3, GPAT2 and 4 moreperoxisome, cytosol

• N-octadecanoylsphing-4-enineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)

  Catalysed by ACAA1, MYO5B, CERS1, TLCD3B and 2 moreperoxisome, cytosol

• N-(hexadecanoyl)-sphing-4-enine-1-phosphateReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. sphing-4-enine + hexadecanoyl-CoA = N-hexadecanoylsphing-4-enine + CoA + H(+)
  3. N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)

  Catalysed by SCP2, HADHB, CERS6, TLCD3B and 3 more

• 1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
  3. 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

  Catalysed by SCP2, HADHB, PRDX6, LPCAT3 and 14 moreOne of 8 routes

• 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. fatty-acyl-CoA synthase (N-C18:0CoA)
  3. octadecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA

  Catalysed by ACAA1, MYO5B, LPCAT3peroxisome, cytosol

• 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA
  3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine

  Catalysed by SCP2, HADHB, PRDX6, LPCAT3 and 2 more

• 1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
  3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine

  Catalysed by SCP2, HADHB, LPGAT1, PLA2G15One of 2 routes

• 1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
  1. hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA
  2. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
  3. 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)

  Catalysed by SCP2, HADHB, LPCAT3, LPCAT1 and 1 more

• (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (EPA)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 10 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (DPA)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 7 routes

• 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphateReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA

  Catalysed by ACAA1, MYO5B, SCD, MBOAT2peroxisome, cytosolOne of 2 routes

• 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
  3. 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA

  Catalysed by ACAA1, MYO5B, SCD, MBOAT2peroxisome, cytosol

• 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholineReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
  3. (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA

  Catalysed by ACAA1, MYO5B, SCD, LPCAT3 and 1 moreperoxisome, cytosol

• (9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (linolenate)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 8 routes

• (13Z)-docosenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 7 routes

• (11Z)-eicosenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 8 routes

• (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
  1. acetyl-CoA C-acyltransferase (3-oxooctadecanoyl-CoA)
  2. Palmitoyl-CoA hydrolase
  3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)

  Catalysed by ACAA1, MYO5B, ACOT7, BAAT and 11 moreperoxisome, cytosolOne of 6 routes