Compound
N-octadecanoylsphing-4-enine
A N-acylsphingosine in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl).
Definition from ChEBI (CHEBI:72961), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C36H71NO3
- Mass
- 565.968 g/mol
- Charge
- 0
- InChIKey
- VODZWWMEJITOND-NXCSZAMKSA-N
- SMILES
- CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCCCCCCCCCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- CERT1ProteinUNIPROT:Q9Y5P4transported byInferred only47 paths47 endpoints
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only26 paths26 endpoints
- GBA1ProteinUNIPROT:P04062substrate ofInferred only16 paths16 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- ACER2ProteinUNIPROT:Q5QJU3substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: N-octadecanoylsphing-4-enine · Sources: Rhea
- N-octadecanoylsphing-4-enine is a substrate of ACER2ProteinRhea RHEA:41279Inferred only
- N-octadecanoylsphing-4-enine is a substrate of ASAH1ProteinRhea RHEA:41279Inferred only
- N-octadecanoylsphing-4-enine is a substrate of ASAH2ProteinRhea RHEA:41279Inferred only
- N-octadecanoylsphing-4-enine is a substrate of GBA1ProteinRhea RHEA:70311Inferred only
- N-octadecanoylsphing-4-enine is transported by CERT1ProteinRhea RHEA:85991Inferred only
Reactions
7 reactions
sphing-4-enine+octadecanoyl-CoAN-octadecanoylsphing-4-enine+coenzyme A(4-)+hydron
Catalysed by CERS1 or TLCD3B or CERS2 or CERS4
Reaction pageLeft to rightBalanced
Rhea RHEA:36691CC BY 4.0Reference data
N-octadecanoylsphing-4-enine+watersphing-4-enine+octadecanoate
Catalysed by ASAH1 or ACER2 or ASAH2
Reaction pageReversibleBalanced
Rhea RHEA:41279CC BY 4.0Reference data
N-(octadecanoyl)-sphing-4-enine-1-phosphocholine+waterN-octadecanoylsphing-4-enine+phosphocholine+hydron
Catalysed by SMPD1
Reaction pageLeft to rightBalanced
Rhea RHEA:54284CC BY 4.0Reference data
beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine+waterN-octadecanoylsphing-4-enine+D-glucose
Catalysed by GBA3
Reaction pageLeft to rightBalanced
Rhea RHEA:59284CC BY 4.0Reference data
beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine+waterN-octadecanoylsphing-4-enine+D-galactose
Catalysed by GBA3
Reaction pageLeft to rightBalanced
Rhea RHEA:59292CC BY 4.0Reference data
beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine+cholesterolcholesteryl 3-beta-D-glucoside+N-octadecanoylsphing-4-enine
Catalysed by GBA1
Reaction pageReversibleBalanced
Rhea RHEA:70311CC BY 4.0Reference data
N-octadecanoylsphing-4-enineN-octadecanoylsphing-4-enine
Transported by CERT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:85991CC BY 4.0Reference data
Where it reaches
8 systems, 19 regions, 42 tissues, 42 transporter routes — routes, not measurements: transporters known to carry N-octadecanoylsphing-4-enine are expressed there, and no source reports it arriving.
Loading the model…
Other names
15 names
Resolves to: N-octadecanoylsphing-4-enine
- Also called
- C18 CerCer 36:1;O2Cer(d18:1(4E)/18:0)Cer(d18:1/18:0)Cer[NS]Ceramide (d18:1/18:0)N-(octadecanoyl)-ceramideN-(octadecanoyl)-sphing-4-enineN-(octadecanoyl)ceramideN-(octadecanoyl)sphing-4-enineN-(stearoyl)-ceramideN-(stearoyl)ceramideN-stearoylsphing-4-enineN-stearoylsphingosine
- Systematic name
- N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]octadecanamide