Compound

(2E)-tetradecenoyl-CoA

An acyl-CoA oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of trans-tetradec-2-enoyl-CoA; major species at pH 7.3.

Definition from ChEBI (CHEBI:61405), read 2026-09-23. CC BY 4.0.

CHEBI:61405ChEBI

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Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound, anion
Formula: C35H56N7O17P3S
Mass: 971.854 g/mol
Charge: -4
InChIKey: MBCVYCOKMMMWLX-YYMFEJJQSA-J
SMILES: CCCCCCCCCCC/C=C/C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)([O-])[O-]
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

5 entities

5 entities reached.

0 reported hops5 assembled from the scaffold

What the reference databases state

Statements

17 statements

17 statements · 2 reference databases · Subject: (2E)-tetradecenoyl-CoA · Sources: Human-GEM, Rhea

Order

(3Z)-tetradecenoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundRhea RHEA:29847Inferred only
(2E)-tetradecenoyl-CoA is converted to tetradecanoyl-CoACompoundRhea RHEA:44968Inferred only
tetradecanoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundHuman-GEM MAR02183Inferred only
tetradecanoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundHuman-GEM MAR03082Inferred only
tetradecanoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundHuman-GEM MAR03128Inferred only
tetradecanoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundRhea RHEA:28358Inferred only
(2E)-tetradecenoyl-CoA is converted to tetradecanoyl-CoACompoundRhea RHEA:28358Inferred only
tetradecanoyl-CoA is converted to (2E)-tetradecenoyl-CoACompoundRhea RHEA:40183Inferred only
(2E)-tetradecenoyl-CoA is converted to tetradecanoyl-CoACompoundHuman-GEM MAR02183Inferred only
(2E)-tetradecenoyl-CoA is a substrate of ECI1ProteinHuman-GEM MAR03083Inferred only
(2E)-tetradecenoyl-CoA is a substrate of ECI2ProteinHuman-GEM MAR03083Inferred only
(2E)-tetradecenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR03083Inferred only

Show the remaining 5

(2E)-tetradecenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03129Inferred only
(2E)-tetradecenoyl-CoA is a substrate of HADHAProteinRhea RHEA:31171Inferred only
(2E)-tetradecenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR03083Inferred only
(2E)-tetradecenoyl-CoA is a substrate of MECRProteinHuman-GEM MAR02183Inferred only
(2E)-tetradecenoyl-CoA is a substrate of PECRProteinRhea RHEA:44968Inferred only

Reactions

13 reactions

tetradecanoyl-CoA+NADP(3-)(2E)-tetradecenoyl-CoA+proton+NADPH(4-)
Catalysed by MECR
Reaction pageReversibleBalancedEC 1.3.1.38mitochondrial matrix
Human-GEM MAR02183CC BY 4.0Reference data
FAD+tetradecanoyl-CoA(2E)-tetradecenoyl-CoA+FADH2
Catalysed by ACOX3 or ACOX1
Reaction pageLeft to rightBalancedEC 1.3.3.6peroxisome
Human-GEM MAR03082CC BY 4.0Reference data
(2E)-tetradecenoyl-CoA+waterMAM00178x
Catalysed by ECI2 & HADHA & ECI1 & EHHADH
Reaction pageLeft to rightBalancedEC 4.2.1.17peroxisome
Human-GEM MAR03083CC BY 4.0Reference data
FAD+tetradecanoyl-CoA(2E)-tetradecenoyl-CoA+FADH2
Catalysed by ACADVL or ACOX3 or ACADL or ACADM or ACOX1 or ACAD9
Reaction pageLeft to rightBalancedEC 1.3.8.7, 1.3.8.8, 1.3.8.9, 1.3.99.-, 1.3.3.6mitochondrial matrix
Human-GEM MAR03128CC BY 4.0Reference data
(2E)-tetradecenoyl-CoA+waterMAM00178m
Catalysed by HADHA
Reaction pageLeft to rightBalancedEC 4.2.1.17mitochondrial matrix
Human-GEM MAR03129CC BY 4.0Reference data
tetradecanoyl-CoA+FAD(3-)+hydron(2E)-tetradecenoyl-CoA+FADH2(2-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:28358CC BY 4.0Reference data
(2E)-tetradecenoyl-CoA(3Z)-tetradecenoyl-CoA
Catalysed by ECI2 or ECI1
Reaction pageRight to leftBalanced
Rhea RHEA:29847CC BY 4.0Reference data
CHEBI:62614(2E)-tetradecenoyl-CoA+water
Catalysed by HADHA
Reaction pageRight to leftBalanced
Rhea RHEA:31171CC BY 4.0Reference data
tetradecanoyl-CoA+dioxygen(2E)-tetradecenoyl-CoA+hydrogen peroxide
Catalysed by ACOX1
Reaction pageLeft to rightBalanced
Rhea RHEA:40183CC BY 4.0Reference data
(2E)-tetradecenoyl-CoA+NADPH(4-)+hydrontetradecanoyl-CoA+NADP(3-)
Catalysed by PECR
Reaction pageLeft to rightBalanced
Rhea RHEA:44968CC BY 4.0Reference data
tetradecanoyl-CoA+oxidized [electron-transfer flavoprotein]+hydron(2E)-tetradecenoyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACADM or ACADL or ACADVL or ACAD9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:47316CC BY 4.0Reference data
CHEBI:87710(2E)-tetradecenoyl-CoA
Catalysed by ECI2 or ECI1
Reaction pageLeft to rightBalanced
Rhea RHEA:47476CC BY 4.0Reference data

Show the remaining 1

Other names

2 names

Resolves to: (2E)-tetradecenoyl-CoA

Also called: trans-2-tetradecenoyl-coenzyme A tetraaniontrans-tetradec-2-enoyl-CoA tetraanion