Pathway
Purine catabolism
The purine bases guanine and hypoxanthine (derived from adenine by events in the purine salvage pathways) are converted to xanthine and then to urate uric acid, which is excreted from the body. The end-point of this pathway in humans and hominoid primates is unusual. Most other mammals metabolize uric acid further to yield more soluble end products, and much speculation has centered on possible roles for high uric acid levels in normal human physiology.
REACT:R-HSA-74259Reactome
What the reference databases state
Statements
14 statements
14 statements · 1 reference database · Subject: Purine catabolism · Sources: Reactome
- ADPRM participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- DNPH1 participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- GDA participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- ITPA participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NT5C participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NT5C1A participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NT5C1B participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NT5C2 participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NT5E participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NUDT15 participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NUDT16 participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- NUDT5 participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
Show the remaining 2
- PNP participates in Purine catabolismProteinReactome R-HSA-74259Inferred only
- XDH participates in Purine catabolismProteinReactome R-HSA-74259Inferred only