Compound
methylamine
The conjugate acid of methylamine; major species at pH 7.3.
Definition from ChEBI (CHEBI:59338), read 2026-09-23. CC BY 4.0.
Structure
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- Class
- Organic compound, cation
- Formula
- CH6N
- Mass
- 32.066 g/mol
- Charge
- +1
- InChIKey
- BAVYZALUXZFZLV-UHFFFAOYSA-O
- SMILES
- C[NH3+]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
12 entities
12 entities reached.
0 reported hops12 assembled from the scaffold
- RHCGProteinUNIPROT:Q9UBD6transported byInferred only36 paths17 endpoints
- MAOAProteinUNIPROT:P21397metabolized byInferred only36 paths36 endpoints
- AQP8ProteinUNIPROT:O94778transported byInferred only14 paths6 endpoints
- MAOBProteinUNIPROT:P27338metabolized byInferred only13 paths13 endpoints
- AOC1ProteinUNIPROT:P19801substrate ofInferred only12 paths12 endpoints
- AOC3ProteinUNIPROT:Q16853substrate ofInferred only10 paths5 endpoints
- CLDN10ProteinUNIPROT:P78369transported byInferred only9 paths9 endpoints
- RHBGProteinUNIPROT:Q9H310transported byInferred only8 paths4 endpoints
- CLDN15ProteinUNIPROT:P56746transported byInferred only6 paths6 endpoints
- CLDN2ProteinUNIPROT:P57739transported byInferred only6 paths5 endpoints
- AOC2ProteinUNIPROT:O75106substrate ofInferred only3 paths3 endpoints
- RHAGProteinUNIPROT:Q02094transported byInferred only2 paths2 endpoints
What the reference databases state
Statements
20 statements
20 statements · 2 reference databases · Subject: methylamine · Sources: Human-GEM, Rhea
- formaldehyde is converted to methylamineCompoundRhea RHEA:76823Inferred only
- methylamine is converted to formaldehydeCompoundHuman-GEM MAR08529Inferred only
- methylamine is converted to formaldehydeCompoundRhea RHEA:59420Inferred only
- methylamine is converted to formaldehydeCompoundRhea RHEA:76823Inferred only
- methylamine is metabolised by MAOAProteinRhea RHEA:51168Inferred only
- methylamine is metabolised by MAOBProteinRhea RHEA:51168Inferred only
- methylamine is a substrate of AOC1ProteinHuman-GEM MAR08529Inferred only
- methylamine is a substrate of AOC2ProteinHuman-GEM MAR08529Inferred only
- methylamine is a substrate of AOC3ProteinHuman-GEM MAR08529Inferred only
- methylamine is a substrate of AOC3ProteinRhea RHEA:59420Inferred only
- methylamine is transported by AQP8ProteinRhea RHEA:74391Inferred only
- methylamine is transported by AQP8ProteinHuman-GEM MAR11775Inferred only
Show the remaining 8
- methylamine is transported by CLDN10ProteinRhea RHEA:74391Inferred only
- methylamine is transported by CLDN15ProteinRhea RHEA:74391Inferred only
- methylamine is transported by CLDN2ProteinRhea RHEA:74391Inferred only
- methylamine is transported by RHAGProteinRhea RHEA:74391Inferred only
- methylamine is transported by RHBGProteinRhea RHEA:74391Inferred only
- methylamine is transported by RHBGProteinHuman-GEM MAR11803Inferred only
- methylamine is transported by RHCGProteinRhea RHEA:74391Inferred only
- methylamine is transported by RHCGProteinHuman-GEM MAR11803Inferred only
Reactions
35 reactions
CHEBI:28918+water+dioxygenMAM00726c+hydrogen peroxide+methylamine
Reaction pageLeft to rightBalancedEC 1.4.3.4cytosol
Human-GEM MAR06745CC BY 4.0Reference data
water+N(2)-[4-(indol-3-yl)butanoyl]-L-glutamine+dioxygenMAM00820c+hydrogen peroxide+methylamine
Reaction pageLeft to rightBalancedEC 1.4.3.4cytosol
Human-GEM MAR06747CC BY 4.0Reference data
water+methylamine+dioxygenformaldehyde+proton+hydrogen peroxide+ammonium
Catalysed by AOC1 or AOC3 or AOC2
Reaction pageLeft to rightBalancedEC 1.4.3.21, 1.4.3.22cytosol
Human-GEM MAR08529CC BY 4.0Reference data
Transported by AQP8
Reaction pageReversibleBalancedEC 7.6.2.2cytosol, extracellular space
Human-GEM MAR11775CC BY 4.0Reference data
proton+methylamineproton+methylamine
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR11803CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR11934CC BY 4.0Reference data
dimethylamine+oxidized [electron-transfer flavoprotein]+water+hydronmethylamine+reduced [electron-transfer flavoprotein]+formaldehyde
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10204CC BY 4.0Reference data
CHEBI:57840+waterurea+methylamine
Reaction pageDirection not assertedBalanced
Rhea RHEA:11764CC BY 4.0Reference data
CHEBI:22191+methylamine+[thioredoxin]-disulfide+watersarcosine+[thioredoxin]-dithiol+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:12825CC BY 4.0Reference data
sarcosine+dioxygen+watermethylamine+glyoxylate+hydrogen peroxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:15165CC BY 4.0Reference data
methylamine+L-glutamate(1-)CHEBI:29083+ammonium
Reaction pageDirection not assertedBalanced
Rhea RHEA:15837CC BY 4.0Reference data
N(6)-methyl-AMP+water+hydronIMP+methylamine
Catalysed by MAPDA
Reaction pageLeft to rightBalanced
Rhea RHEA:16001CC BY 4.0Reference data
Where it reaches
8 systems, 12 regions, 34 tissues, 43 transporter routes — routes, not measurements: transporters known to carry methylamine are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: methylamine
- Also called
- methanaminium cationmethylaminium cation
- Systematic name
- methanaminium