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Proteins/UNIPROT:Q6NUT3
Transporter that mediates the import of cysteine into melanosomes, thereby regulating skin pigmentation. In melanosomes, cysteine import is required both for normal levels of cystine, the oxidized dimer of cysteine, and provide cysteine for the production of the cysteinyldopas used in pheomelanin synthesis, thereby regulating skin pigmentation. Also catalyzes import of cysteine into lysosomes in non-pigmented cells, regulating lysosomal cystine and cysteine storage, which is essential for redox homeostasis..
Function from UniProtKB (Q6NUT3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
20 statements
20 statements · 4 reference databases · Subject: MFSD12 · Sources: Bgee, gene ontology, Hetionet, Rhea
1 reaction
Transported by MFSD12 or SFXN1
Reaction pageLeft to rightBalanced
Rhea RHEA:29655CC BY 4.0Reference data
2 names
Resolves to: MFSD12