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Proteins/UNIPROT:Q8TDX6
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation and subsequent endochondral ossification. Moreover, is involved in the metabolism of aggrecan (By similarity)..
Function from UniProtKB (Q8TDX6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
117 statements
117 statements · 5 reference databases · Subject: CSGALNACT1 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
6 reactions
MAM00762g+MAM03110gMAM01568g+proton+UDP
Catalysed by CSGALNACT1 or CSGALNACT2
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.174Golgi apparatus
Human-GEM MAR07206CC BY 4.0Reference data
MAM01564g+CHEBI:16264MAM01565g+proton+UDP
5 names
Resolves to: CSGALNACT1
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07494CC BY 4.0Reference data
MAM01515g+CHEBI:16264MAM01516g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07496CC BY 4.0Reference data
MAM01540g+CHEBI:16264MAM01541g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07521CC BY 4.0Reference data
MAM01551g+CHEBI:16264MAM01552g+proton+UDP
Catalysed by CHPF or CHSY1 or CSGALNACT1 or CSGALNACT2 or CHSY3
Reaction pageLeft to rightBalance undeterminableEC 2.4.1.226Golgi apparatus
Human-GEM MAR07536CC BY 4.0Reference data
3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein]+UDP-N-acetyl-alpha-D-galactosamine3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein]+UDP+hydron
Catalysed by CSGALNACT2 or CSGALNACT1
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:23464CC BY 4.0Reference data