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Proteins/UNIPROT:Q9UHJ9
Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain. May catalyze the second step of the fatty acid remodeling, by reacylating a lyso-GPI intermediate at sn-2 of inositol phosphate by a saturated chain (By similarity). The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts..
Function from UniProtKB (Q9UHJ9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
15 statements
15 statements · 4 reference databases · Subject: PGAP2 · Sources: Bgee, Hetionet, Rhea, WikiPathways
1 reaction
[protein]-C-terminal carboxyl phosphoethanolamide-lysoGPI(deacylinositol-H7)+octadecanoyl-CoA[protein]-C-terminal carboxyl phosphoethanolamide-(1-radyl,2-octadecanoyl)-GPI(deacylinositol-H7)+coenzyme A(4-)
Catalysed by PGAP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:83851CC BY 4.0Reference data
3 names
Resolves to: PGAP2