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Proteins/UNIPROT:Q5T3J3
Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells..
Function from UniProtKB (Q5T3J3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
177 statements
177 statements · 2 reference databases · Subject: LRIF1 · Sources: gene ontology, Hetionet
5 names
Resolves to: LRIF1