Loading the page.
Proteins/UNIPROT:Q32P41
Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding..
Function from UniProtKB (Q32P41), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
121 statements
121 statements · 4 reference databases · Subject: TRMT5 · Sources: Bgee, Hetionet, Human Protein Atlas, Reactome
1 reaction
CHEBI:74269+S-adenosyl-L-methionineCHEBI:73542+S-adenosyl-L-homocysteine+hydron
Catalysed by TRMT5
Reaction pageDirection not assertedBalanced
Rhea RHEA:36899CC BY 4.0Reference data
6 names
Resolves to: TRMT5