Compound
(17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate
A 17,18-EETeTr(1−) in which the epoxy group has (17S,18R)-configuration.
Definition from ChEBI (CHEBI:76635), read 2026-09-23. CC BY 4.0.
CHEBI:76635ChEBI
Structure
- Class
- Organic compound, anion
- Formula
- C20H29O3
- Mass
- 317.449 g/mol
- Charge
- -1
- InChIKey
- GPQVVJQEBXAKBJ-YQLHGUCYSA-M
- SMILES
- CC[C@H]1O[C@H]1C/C=CC/C=CC/C=CC/C=CCCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate · Sources: Rhea
- (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate is metabolised by CYP2C8ProteinRhea RHEA:39783Inferred only
- (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate is metabolised by CYP2D6ProteinRhea RHEA:39783Inferred only
- (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate is metabolised by CYP2J2ProteinRhea RHEA:39783Inferred only
Reactions
1 reaction
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+reduced [NADPH--hemoprotein reductase]+dioxygen(17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP2C8 or CYP2D6 or CYP2J2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:39783CC BY 4.0Reference data
Other names
5 names
Resolves to: (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate
- Also called
- (17S,18R)-Ep-(5Z,8Z,11Z,14Z)-ETE(17S,18R)-EpETE(5Z,8Z,11Z,14Z,17S,18R)-17,18-epoxyeicosatetraenoate(5Z,8Z,11Z,14Z,17S,18R)-17,18-epoxyicosatetraenoate
- Systematic name
- (5Z,8Z,11Z,14Z)-16-[(2S,3R)-3-ethyloxiran-2-yl]hexadeca-5,8,11,14-tetraenoate