Compound
(5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate
A polyunsaturated fatty acid anion that is the conjugate base of 12-HPEPE, obtained by deprotonation of the carboxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:78078), read 2026-09-23. CC BY 4.0.
CHEBI:78078ChEBI
Structure
- Class
- Organic compound, anion
- Formula
- C20H29O4
- Mass
- 333.448 g/mol
- Charge
- -1
- InChIKey
- HDMYXONNVAOHFR-QGQBRVLBSA-M
- SMILES
- CC/C=CC/C=CCC(/C=C/C=CC/C=CCCCC(=O)[O-])OO
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
- ALOX12BProteinUNIPROT:O75342substrate ofInferred only8 paths8 endpoints
- all-cis-5,8,11,14,17-icosapentaenoic acidCompoundCHEBI:28364converted toInferred only7 paths7 endpoints
What the reference databases state
Chemical structure
- (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate has the functional parent (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateCompoundChEBI CHEBI:78078Inferred only
Statements
3 statements
3 statements · 1 reference database · Subject: (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate · Sources: Rhea
- (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate is converted to all-cis-5,8,11,14,17-icosapentaenoic acidCompoundRhea RHEA:41344Inferred only
- all-cis-5,8,11,14,17-icosapentaenoic acid is converted to (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoateCompoundRhea RHEA:41344Inferred only
- (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate is a substrate of ALOX12BProteinRhea RHEA:41344Inferred only
Reactions
1 reaction
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+dioxygen(5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate
Catalysed by ALOX12B
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:41344CC BY 4.0Reference data
Other names
5 names
Resolves to: (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate
- Also called
- (5Z,8Z,10E,14Z,17Z)-12-hydroperoxyicosapentaenoate12-Hp-(5Z,8Z,10E,14Z,17Z)-EPE12-HpEPE12-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate
- Systematic name
- (5Z,8Z,10E,14Z,17Z)-12-hydroperoxyicosa-5,8,10,14,17-pentaenoate