(13S)-hydroperoxy-(9Z,11E)-octadecadienoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

112 compounds within 3 steps: 6 in 1, 7 in 2, 99 in 3

One step

11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoateReach from here →
1. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoate
Catalysed by ALOXE3
ferrocytochrome cReach from here →
1. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion
No catalyst recordedcytosol
nonanoateReach from here →
1. 13(S)-HPODE hydrolysis
No catalyst recordedcytosol
glutathione disulfideReach from here →
1. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
Catalysed by GPX1, GSTA1, GPX2, GPX4
13-oxo-(9Z,11E)-octadecadienoateReach from here →
1. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 13-oxo-(9Z,11E)-octadecadienoate + H2O
Catalysed by CYP1A1, CYP1A2, CYP1B1, CYP2S1 and 1 more
(13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. glutathione peroxidase (13(S)-HPODE)
Catalysed by GPX5, GPX1, GPX2, GPX3 and 5 morecytosolOne of 2 routes

Two steps

15(S)-HPETEReach from here →
1. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
2. Glutathione: 15-HPETE oxidoreductase
Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosol
ferricytochrome cReach from here →
1. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion
2. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion
No catalyst recordedcytosolOne of 4 routes
L-cystineReach from here →

Three steps

Catalysed by GPX1, GSTA1, GPX2, GPX4cytosol

CHEBI:16856Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosolOne of 7 routes

methylarsonateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 more

thiosulfateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 1 more

glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 1 moreOne of 4 routes

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 1 more

tauroursodeoxycholateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 3 routes

glycoursodeoxycholateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 3 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosolOne of 2 routes

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 26 morecytosolOne of 5 routes

prostaglandin E3Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 7 morecytosol, extracellular spaceOne of 2 routes

prostaglandin A2Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 7 morecytosol, extracellular spaceOne of 2 routes

prostaglandin B1Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 7 morecytosol, extracellular spaceOne of 2 routes

leukotriene F4Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosol, extracellular spaceOne of 2 routes

prostaglandin A2-S-(R)-glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 more

prostaglandin A2-S-(S)-glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 3 more

prostaglandin J2-S-(R)-glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 3 more

prostaglandin J2-S-(S)-glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 3 more

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 5 more

(13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 3 more

S-methyl glutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 more

L-cystine-bis-glycineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 morecytosol

S-adenosylglutathioneReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 more

acetylcholineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 2 routes

pyruvateReach from here →

Catalysed by LDHDcytosol, mitochondrial matrixOne of 3 routes

(S)-malateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 moremitochondrial matrix, cytosolOne of 2 routes

L-leucineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 morecytosol, extracellular space

CHEBI:15650Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 7 morecytosol, extracellular spaceOne of 2 routes

bromideReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 22 morecytosolOne of 2 routes

a halide anionReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 23 more

sulfateReach from here →

Catalysed by SUOXcytosol, mitochondrial matrixOne of 4 routes

lithocholic acidReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 2 routes

ubiquinonesReach from here →

Catalysed by UQCRQ, UQCR11, MT-CYB, UQCRH and 6 morecytosol, mitochondrial intermembrane space, mitochondrial matrix

L-arginineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 1 morecytosol, inner side of the membrane, outer side of the membrane

bilirubin IXalphaReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 2 routes

taurolithocholateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 8 morecytosol, extracellular spaceOne of 2 routes

CHEBI:17208Reach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosol

homocysteineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosol

sulfiteReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 moreOne of 6 routes

L-cysteineReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosolOne of 4 routes

urateReach from here →

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 2 moreinner side of the membrane, outer side of the membrane