nonanoate

1. 13(S)-HPODE hydrolysis

No catalyst recordedcytosol

1. 13(S)-HPODE hydrolysis
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoate

Catalysed by ALOXE3cytosol

1. 13(S)-HPODE hydrolysis
2. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion

No catalyst recordedcytosol

1. 13(S)-HPODE hydrolysis
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O

Catalysed by GPX1, GSTA1, GPX2, GPX4cytosol

1. 13(S)-HPODE hydrolysis
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 13-oxo-(9Z,11E)-octadecadienoate + H2O

Catalysed by CYP1A1, CYP1A2, CYP1B1, CYP2S1 and 1 morecytosol

1. 13(S)-HPODE hydrolysis
2. glutathione peroxidase (13(S)-HPODE)

Catalysed by GPX5, GPX1, GPX2, GPX3 and 5 morecytosolOne of 2 routes

1. 13(S)-HPODE hydrolysis
2. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
3. Glutathione: 15-HPETE oxidoreductase

Catalysed by GPX1, GSTA1, GPX2, GPX4 and 6 morecytosol

1. 13(S)-HPODE hydrolysis
2. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion
3. 13(S)-HPODE to 13-oxy-radical-octadecadienoate conversion