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Proteins/UNIPROT:P15289
Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein saposin B. Also involved in the catabolism of other sulfoglycosphingolipids such as SB1a and SM3 (beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) (By similarity)..
Function from UniProtKB (P15289), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
65 statements
65 statements · 8 reference databases · Subject: ARSA · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
3 reactions
water+an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineCHEBI:12947+proton+sulfate
Catalysed by ARSD or ARSA or ARSL
Reaction pageLeft to rightBalance undeterminableEC 3.1.6.8lysosome
Human-GEM MAR00790CC BY 4.0Reference data
water+MAM02947lCHEBI:12947+proton+sulfate
3 names
Resolves to: ARSA
Catalysed by ARSA
Reaction pageLeft to rightBalance undeterminableEC 3.1.6.8lysosome
Human-GEM MAR08209CC BY 4.0Reference data
an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine+watera beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine+sulfate+hydron
Catalysed by ARSA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:21300CC BY 4.0Reference data