Pathway
Phenylalanine and tyrosine metabolism
The hydroxylation of phenylalanine, an essential amino acid, to form tyrosine is a major source of the latter amino acid in the body under normal conditions and is also the first step in phenylalanine catabolism. To continue the catabolic process, tyrosine is transaminated to 3-(4-hydroxyphenyl)pyruvate which is broken down to fumarate and acetoacetate.
REACT:R-HSA-8963691Reactome
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: Phenylalanine and tyrosine metabolism · Sources: Reactome
- ASRGL1 participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- FAH participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- GSTZ1 participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- HGD participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- HPD participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- IL4I1 participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- KYAT1 participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- PAH participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- PCBD1 participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- QDPR participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only
- TAT participates in Phenylalanine and tyrosine metabolismProteinReactome R-HSA-8963691Inferred only