D-aspartate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

303 compounds within 3 steps: 3 in 1, 39 in 2, 261 in 3

Three steps

decanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. medium-chain acyl-CoA ligase (decanoic acid)
Catalysed by DDO, CS, ACSM4, ACSM1 and 4 moremitochondrial matrix, cytosolOne of 7 routes
(2E)-hexadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Carnitine O-Palmitoyltransferase
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 4 routes
(9Z)-hexadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (palmitolate)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 11 routes
(4R)-4-hydroxy-2-oxoglutarateReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. Oxaloacetate Decarboxylase
3. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by DDO, FAHD1, HOGA1cytosol
3-hydroxyisovaleryl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)
Catalysed by DDO, CS, CPT1A, CPT1Bmitochondrial matrix, cytosol
CHEBI:63544Reach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (adrenic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes
ubiquinol-10Reach from here →
1. D-aspartate(in) + sulfate(out) = D-aspartate(out) + sulfate(in)
2. sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)
3. ubiquinone-10 + hydrogen sulfide + sulfite + 2 H(+) = ubiquinol-10 + thiosulfate
Catalysed by SLC25A14, SLC25A30, SQORinner side of the membrane, outer side of the membrane
hexacosanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (cerotic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
tetracosanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (lignocerate)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 10 routes
docosanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (behenic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 9 routes
(2E)-octadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Carnitine O-Palmitoyltransferase
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 3 routes
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (stearidonic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 8 routes
(4S)-4-hydroxy-2-oxoglutarateReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. Oxaloacetate Decarboxylase
3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by DDO, FAHD1, HOGA1cytosol
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 6 routes
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 3 routes
dodecanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Activation of dodecanedioic acid
Catalysed by DDO, CSmitochondrial matrix, cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Production of Sebacoylcarnitine
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Production of Suberylcarnitine
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by DDO, CSmitochondrial matrix, cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 5 routes
beta-citrylglutamateReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. citrate + L-glutamate + ATP = beta-citrylglutamate + ADP + phosphate + H(+)
Catalysed by DDO, CS, RIMKLBmitochondrial matrix
4,8-dimethylnonanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by DDO, CS, CRAT, CROTmitochondrial matrix, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by DDO, CS, ACAA1, HSD17B4 and 2 moremitochondrial matrix, peroxisome
hexadecanedioyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Production of Hexadecanedioylcarnitine
Catalysed by DDO, CS, CPT1A, CPT1C and 1 moremitochondrial matrix, cytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. fatty-acid-CoA ligase
Catalysed by DDO, CS, SLC27A2mitochondrial matrix, cytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by DDO, CS, ACSM4, ACSM1 and 4 moremitochondrial matrix, cytosolOne of 3 routes
thio-Mo-molybdopterinReach from here →
1. D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)
2. K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by SLC1A7, SLC1A3, SLC1A2, SLC1A1 and 2 moreinner side of the membrane, outer side of the membrane
(5Z)-tetradecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by DDO, CS, ACADM, ECHS1 and 2 moremitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by DDO, CS, HADHA, ACAA2 and 1 moremitochondrial matrix
16alpha-hydroxydehydroepiandrosterone 3-sulfateReach from here →
1. D-aspartate(in) + sulfate(out) = D-aspartate(out) + sulfate(in)
2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
3. dehydroepiandrosterone 3-sulfate + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxydehydroepiandrosterone 3-sulfate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by SLC25A14, SLC25A30, STS, CYP3A7inner side of the membrane, outer side of the membrane
(7Z)-hexadecenoyl-CoAReach from here →
1. D-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)
2. acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by DDO, CS, SLC27A2, ACSL4 and 6 moremitochondrial matrix, cytosolOne of 8 routes