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Proteins/UNIPROT:Q99489
Selectively catalyzes the oxidative deamination of acidic amino acids. Suppresses the level of D-aspartate in the brain, an amino acid that can act as an agonist for glutamate receptors. Protects the organism from the toxicity of D-amino acids (By similarity). May also function in the intestine (By similarity)..
Function from UniProtKB (Q99489), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
54 statements
54 statements · 7 reference databases · Subject: DDO · Sources: gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt
4 reactions
D-aspartic acid+FAD+waterFADH2+proton+ammonium+oxaloacetate
Catalysed by DDO
Reaction pageLeft to rightBalancedEC 1.4.3.1peroxisome
Human-GEM MAR07641CC BY 4.0Reference data
FADH2+dioxygenFAD+hydrogen peroxide
Catalysed by
2 names
Resolves to: DDO
Reaction pageLeft to rightBalancedperoxisome
Human-GEM MAR20114CC BY 4.0Reference data
CHEBI:29986+dioxygen+water2-oxoglutarate(2-)+hydrogen peroxide+ammonium
Catalysed by DDO
Reaction pageLeft to rightBalanced
Rhea RHEA:10028CC BY 4.0Reference data
D-aspartate+dioxygen+wateroxaloacetate+hydrogen peroxide+ammonium
Catalysed by DDO
Reaction pageLeft to rightBalanced
Rhea RHEA:12512CC BY 4.0Reference data