hypochlorous acid

Three steps

• 5-phospho-beta-D-ribosylamineReach from here →
  1. Peroxidase
  2. Transport of L-Glutamine by Atb0 Transporter
  3. phosphoribosyl pyrophosphate amidotransferase (glutamine)

  Catalysed by LPO, SLC6A14, PPATextracellular space, cytosolOne of 2 routes

• D-glucosamine 6-phosphateReach from here →
  1. Peroxidase
  2. Transport of L-Glutamine by Atb0 Transporter
  3. D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate

  Catalysed by LPO, SLC6A14, GFPT2, GFPT1extracellular space, cytosol

• L-methionine (S)-S-oxideReach from here →
  1. Peroxidase
  2. transport of chloride and methionine (cytosol to extracellular)
  3. [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol

  Catalysed by LPO, SLC6A14, MSRAextracellular space, cytosol

• L-methionine (R)-S-oxideReach from here →
  1. Peroxidase
  2. transport of chloride and methionine (cytosol to extracellular)
  3. [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol

  Catalysed by LPO, SLC6A14, MSRB3, MSRB1 and 1 moreextracellular space, cytosol

• N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)

  Catalysed by LPO, SLC6A9, SLC6A14, GLYATL2extracellular space, cytosolOne of 2 routes

• N-[(R)-4-phosphopantothenoyl]-L-cysteineReach from here →
  1. Peroxidase
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. (R)-4'-phosphopantothenate:L-cysteine ligase

  Catalysed by LPO, SLC6A14, PPCSextracellular space, cytosolOne of 4 routes

• 3-iodo-L-tyrosineReach from here →
  1. Peroxidase
  2. Transport of L-Tyrosine by Atb0 Transporter
  3. thyroid peroxidase (iodine)

  Catalysed by LPO, SLC6A14, TPOextracellular space, cytosolOne of 2 routes

• L-prolineReach from here →
  1. Peroxidase
  2. transport of alanine and chloride (cytosol to extracellular)
  3. L-proline(out) + L-alanine(in) + Na(+)(out) = L-proline(in) + L-alanine(out) + Na(+)(in)

  Catalysed by LPO, SLC6A14, SLC1A4extracellular space, cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

• estrone 3-sulfateReach from here →
  1. Peroxidase
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. estrone 3-sulfate + H2O = estrone + sulfate + H(+)

  Catalysed by LPO, SLC26A6, STSextracellular space, cytosol

• N-benzoylglycineReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. Hippurate (Benzoylglycinate) Formation

  Catalysed by LPO, SLC6A9, SLC6A14extracellular space, cytosol, mitochondrial matrixOne of 2 routes

• 3-sulfino-L-alanineReach from here →
  1. Peroxidase
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. L-Cysteine:oxygen oxidoreductase

  Catalysed by LPO, SLC6A14, CDO1extracellular space, cytosolOne of 2 routes

• L-cysteinylglycineReach from here →
  1. Peroxidase
  2. transport of alanine and chloride (cytosol to extracellular)
  3. gamma-glutamyltransferase (alanine)

  Catalysed by LPO, SLC6A14, GGTLC3, GGT1 and 4 moreextracellular space, cytosolOne of 2 routes

• (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylateReach from here →
  1. Peroxidase
  2. transport of trans-4-hydroxy-L-proline (cytosol to extracellular)
  3. trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase

  Catalysed by LPO, CLTRN, SLC6A20, PYCR1 and 2 moreextracellular space, cytosolOne of 4 routes

• (5-hydroxyindol-3-yl)acetateReach from here →
  1. Peroxidase
  2. transport of chloride and sulfate (cytosol to extracellular)
  3. Transport of 5-Hydroxyindoleacetate

  Catalysed by LPO, SLC26A6, SLC4A1extracellular space, cytosolOne of 2 routes

• N(5)-[(Z)-amino(hydroxyimino)methyl]ornithineReach from here →
  1. Peroxidase
  2. transport of arginine and chloride (cytosol to extracellular)
  3. L-arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)

  Catalysed by LPO, SLC6A14, NOS3, NOS1 and 1 moreextracellular space, cytosol

• Mo-molybdopterinReach from here →
  1. Peroxidase
  2. transport of alanine and chloride (cytosol to extracellular)
  3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

  Catalysed by LPO, SLC6A14, MOCOSextracellular space, cytosol

• (8Z,11Z,14Z)-eicosatrienoateReach from here →
  1. Peroxidase
  2. Carnitine Transport by Atb0
  3. Utilized Transport

  Catalysed by LPO, SLC6A14extracellular space, cytosol, endoplasmic reticulum

• (2S)-2-aminobutanoateReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine

  Catalysed by LPO, SLC6A9, SLC6A14, AGXT2extracellular space, cytosolOne of 2 routes

• O-dodecanoyl-R-carnitineReach from here →
  1. Peroxidase
  2. Carnitine Transport by Atb0
  3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)

  Catalysed by LPO, SLC6A14, CPT1A, CPT1C and 1 moreextracellular space, cytosolOne of 7 routes

• thio-Mo-molybdopterinReach from here →
  1. Peroxidase
  2. transport of chloride and cysteine (cytosol to extracellular)
  3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O

  Catalysed by LPO, SLC6A14, MOCOSextracellular space, cytosol

• glycodeoxycholateReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. Glycodeoxycholate amidohydrolase

  Catalysed by LPO, SLC6A9, SLC6A14extracellular space, cytosolOne of 2 routes

• O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
  1. Peroxidase
  2. Carnitine Transport by Atb0
  3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal

  Catalysed by LPO, SLC6A14, CRAT, CROTextracellular space, cytosol, peroxisomeOne of 5 routes

• N-tetradecanoylglycineReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

  Catalysed by LPO, SLC6A9, SLC6A14, GLYATL2extracellular space, cytosol

• N-eicosanoylglycinateReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)

  Catalysed by LPO, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• N-docosanoylglycineReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

  Catalysed by LPO, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• N-hexacosanoylglycineReach from here →
  1. Peroxidase
  2. transport of chloride and glycine (cytosol to extracellular)
  3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

  Catalysed by LPO, SLC6A9, SLC6A14, BAATextracellular space, cytosol

• an N(2)-acyl-L-glutamineReach from here →
  1. Peroxidase
  2. Transport of L-Glutamine by Atb0 Transporter
  3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)

  Catalysed by LPO, SLC6A14, GLYATL1B, GLYATL1extracellular space, cytosol

• taurochenodeoxycholateReach from here →
  1. Peroxidase
  2. Neurotransmitter:Sodium Symporter (Nss) Tcdb:2.A.22.3.3
  3. 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase

  Catalysed by LPO, SLC6A6, BAATextracellular space, cytosol, peroxisomeOne of 3 routes