Proteins/UNIPROT:Q8N1E6

FBXL14

ProteinUNIPROT:Q8N1E6

Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1..

Function from UniProtKB (Q8N1E6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

35 statements

35 statements · 3 reference databases · Subject: FBXL14 · Sources: gene ontology, Hetionet, Reactome

Order

ABCC1 covaries with FBXL14ProteinHetionet hetionet:covaries:144699-4363Inferred only
ADGRL1 covaries with FBXL14ProteinHetionet hetionet:covaries:144699-22859Inferred only
AP1M1 covaries with FBXL14ProteinHetionet hetionet:covaries:144699-8907Inferred only
RASA3 covaries with FBXL14ProteinHetionet hetionet:covaries:144699-22821Inferred only
RHOB covaries with FBXL14ProteinHetionet hetionet:covaries:144699-388Inferred only
COPS5 interacts with FBXL14ProteinHetionet hetionet:interacts:10987-144699Inferred only
COPS6 interacts with FBXL14ProteinHetionet hetionet:interacts:10980-144699Inferred only
CUL1 interacts with FBXL14ProteinHetionet hetionet:interacts:144699-8454Inferred only
HSP90AA1 interacts with FBXL14ProteinHetionet hetionet:interacts:144699-3320Inferred only
HSP90AB1 interacts with FBXL14ProteinHetionet hetionet:interacts:144699-3326Inferred only
SNAI1 interacts with FBXL14ProteinHetionet hetionet:interacts:144699-6615Inferred only
FBXL14 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only

Show the remaining 23

FBXL14 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
FBXL14 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
FBXL14 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FBXL14 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
FBXL14 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
FBXL14 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
FBXL14 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q8N1E6|GO:0006355Inferred only
ANO10 increases the expression of FBXL14ProteinHetionet hetionet:regulates:55129-144699Inferred only
ANPEP increases the expression of FBXL14ProteinHetionet hetionet:regulates:290-144699Inferred only
ARHGEF5 increases the expression of FBXL14ProteinHetionet hetionet:regulates:7984-144699Inferred only
BID increases the expression of FBXL14ProteinHetionet hetionet:regulates:637-144699Inferred only
BTG2 increases the expression of FBXL14ProteinHetionet hetionet:regulates:7832-144699Inferred only
DIABLO increases the expression of FBXL14ProteinHetionet hetionet:regulates:56616-144699Inferred only
DNAJB1 decreases the expression of FBXL14ProteinHetionet hetionet:regulates:3337-144699Inferred only
HS2ST1 increases the expression of FBXL14ProteinHetionet hetionet:regulates:9653-144699Inferred only
ITGA2 increases the expression of FBXL14ProteinHetionet hetionet:regulates:3673-144699Inferred only
NEK7 increases the expression of FBXL14ProteinHetionet hetionet:regulates:140609-144699Inferred only
NUP93 increases the expression of FBXL14ProteinHetionet hetionet:regulates:9688-144699Inferred only
PJA2 increases the expression of FBXL14ProteinHetionet hetionet:regulates:9867-144699Inferred only
POLR2A increases the expression of FBXL14ProteinHetionet hetionet:regulates:5430-144699Inferred only
SOX3 decreases the expression of FBXL14ProteinHetionet hetionet:regulates:6658-144699Inferred only
TIMM9 increases the expression of FBXL14ProteinHetionet hetionet:regulates:26520-144699Inferred only
TIPARP increases the expression of FBXL14ProteinHetionet hetionet:regulates:25976-144699Inferred only

Other names

3 names

Resolves to: FBXL14

Also called: F-box and leucine-rich repeat protein 14F-box/LRR-repeat protein 14FBL14

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