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Proteins/UNIPROT:Q8TAE8
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
Function from UniProtKB (Q8TAE8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
37 statements
37 statements · 2 reference databases · Subject: GADD45GIP1 · Sources: Hetionet, Reactome
13 names
Resolves to: GADD45GIP1