Biological process
positive regulation of ERK1 and ERK2 cascade
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Definition from the Gene Ontology (GO:0070374), read 2026-09-23. CC BY 4.0.
GO:0070374Gene Ontology
What the reference databases state
Statements
175 statements
175 statements · 1 reference database · Subject: positive regulation of ERK1 and ERK2 cascade · Sources: gene ontology
- ABCA7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8IZY2|GO:0070374Inferred only
- ACKR3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P25106|GO:0070374Inferred only
- ACTA2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P62736|GO:0070374Inferred only
- ADCYAP1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P18509|GO:0070374Inferred only
- ADORA2A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P29274|GO:0070374Inferred only
- ADRA1A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35348|GO:0070374Inferred only
- ADRB3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P13945|GO:0070374Inferred only
- AGER regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q15109|GO:0070374Inferred only
- AKAP12 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q02952|GO:0070374Inferred only
- ALKAL1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6UXT8|GO:0070374Inferred only
- ALOX15 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P16050|GO:0070374Inferred only
- ANGPT1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q15389|GO:0070374Inferred only
Show the remaining 163
- APOE regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P02649|GO:0070374Inferred only
- APP regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P05067|GO:0070374Inferred only
- ARHGAP8 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P85298|GO:0070374Inferred only
- ARRB1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P49407|GO:0070374Inferred only
- ARRB2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P32121|GO:0070374Inferred only
- BMP2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P12643|GO:0070374Inferred only
- BMPER regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8N8U9|GO:0070374Inferred only
- BRAF regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P15056|GO:0070374Inferred only
- C5AR1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P21730|GO:0070374Inferred only
- CALCR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P30988|GO:0070374Inferred only
- CARD9 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9H257|GO:0070374Inferred only
- CASR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P41180|GO:0070374Inferred only
- CCL19 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q99731|GO:0070374Inferred only
- CCL21 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O00585|GO:0070374Inferred only
- CCL3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P10147|GO:0070374Inferred only
- CCN2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P29279|GO:0070374Inferred only
- CCR1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P32246|GO:0070374Inferred only
- CCR7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P32248|GO:0070374Inferred only
- CD36 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P16671|GO:0070374Inferred only
- CD44 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P16070|GO:0070374Inferred only
- CD74 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P04233|GO:0070374Inferred only
- CFLAR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O15519|GO:0070374Inferred only
- CHRNA7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P36544|GO:0070374Inferred only
- CIB1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q99828|GO:0070374Inferred only
- CRKL regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P46109|GO:0070374Inferred only
- CSF1R regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P07333|GO:0070374Inferred only
- CX3CL1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P78423|GO:0070374Inferred only
- DDR2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q16832|GO:0070374Inferred only
- DDT regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P30046|GO:0070374Inferred only
- DENND2B regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P78524|GO:0070374Inferred only
- DNAJC27 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NZQ0|GO:0070374Inferred only
- DRD2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P14416|GO:0070374Inferred only
- DSTYK regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6XUX3|GO:0070374Inferred only
- DUSP15 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9H1R2|GO:0070374Inferred only
- EGFR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P00533|GO:0070374Inferred only
- EPO regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01588|GO:0070374Inferred only
- ERBB4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q15303|GO:0070374Inferred only
- F2R regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P25116|GO:0070374Inferred only
- F2RL1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P55085|GO:0070374Inferred only
- FBXW7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q969H0|GO:0070374Inferred only
- FERMT2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q96AC1|GO:0070374Inferred only
- FFAR4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q5NUL3|GO:0070374Inferred only
- FGA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P02671|GO:0070374Inferred only
- FGB regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P02675|GO:0070374Inferred only
- FGF1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P05230|GO:0070374Inferred only
- FGF19 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O95750|GO:0070374Inferred only
- FGF2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P09038|GO:0070374Inferred only
- FGF21 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NSA1|GO:0070374Inferred only
- FGF23 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9GZV9|GO:0070374Inferred only
- FGF4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P08620|GO:0070374Inferred only
- FGFR2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P21802|GO:0070374Inferred only
- FGFR3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P22607|GO:0070374Inferred only
- FGFR4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P22455|GO:0070374Inferred only
- FGG regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P02679|GO:0070374Inferred only
- FLT4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35916|GO:0070374Inferred only
- FPR2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P25090|GO:0070374Inferred only
- FSHR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P23945|GO:0070374Inferred only
- GAREM1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9H706|GO:0070374Inferred only
- GAS6 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q14393|GO:0070374Inferred only
- GCG regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01275|GO:0070374Inferred only
- GCNT2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8N0V5|GO:0070374Inferred only
- GLIPR2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9H4G4|GO:0070374Inferred only
- GNAI2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P04899|GO:0070374Inferred only
- GPBAR1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8TDU6|GO:0070374Inferred only
- GPER1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q99527|GO:0070374Inferred only
- GPNMB regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q14956|GO:0070374Inferred only
- GPR183 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P32249|GO:0070374Inferred only
- GPR55 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9Y2T6|GO:0070374Inferred only
- HAND2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P61296|GO:0070374Inferred only
- HAVCR2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8TDQ0|GO:0070374Inferred only
- HMGB1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P09429|GO:0070374Inferred only
- HRAS regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01112|GO:0070374Inferred only
- HTR2A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P28223|GO:0070374Inferred only
- HTR2B regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P41595|GO:0070374Inferred only
- HTR2C regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P28335|GO:0070374Inferred only
- ICAM1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P05362|GO:0070374Inferred only
- IGF1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P05019|GO:0070374Inferred only
- IL13 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35225|GO:0070374Inferred only
- IL13RA2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q14627|GO:0070374Inferred only
- IL1B regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01584|GO:0070374Inferred only
- IL26 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NPH9|GO:0070374Inferred only
- INHBA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P08476|GO:0070374Inferred only
- ITGB3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P05106|GO:0070374Inferred only
- KDR regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35968|GO:0070374Inferred only
- LGALS9 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O00182|GO:0070374Inferred only
- MAP2K1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q02750|GO:0070374Inferred only
- MAP2K7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O14733|GO:0070374Inferred only
- MAP3K12 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q12852|GO:0070374Inferred only
- MAPK3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P27361|GO:0070374Inferred only
- MARCO regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9UEW3|GO:0070374Inferred only
- MC5R regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P33032|GO:0070374Inferred only
- MFHAS1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9Y4C4|GO:0070374Inferred only
- MIF regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P14174|GO:0070374Inferred only
- MOS regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P00540|GO:0070374Inferred only
- MT3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P25713|GO:0070374Inferred only
- MTURN regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q8N3F0|GO:0070374Inferred only
- NAMPT regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P43490|GO:0070374Inferred only
- NDRG4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9ULP0|GO:0070374Inferred only
- NECAB2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q7Z6G3|GO:0070374Inferred only
- NELFE regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P18615|GO:0070374Inferred only
- NGF regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01138|GO:0070374Inferred only
- NOD2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9HC29|GO:0070374Inferred only
- NODAL regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q96S42|GO:0070374Inferred only
- NOTCH1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P46531|GO:0070374Inferred only
- NOTCH2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q04721|GO:0070374Inferred only
- NOX4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NPH5|GO:0070374Inferred only
- NPNT regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6UXI9|GO:0070374Inferred only
- NPS regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P0C0P6|GO:0070374Inferred only
- NPSR1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6W5P4|GO:0070374Inferred only
- NPY regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01303|GO:0070374Inferred only
- NPY5R regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q15761|GO:0070374Inferred only
- NRG1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q02297|GO:0070374Inferred only
- NRP1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O14786|GO:0070374Inferred only
- NTRK1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P04629|GO:0070374Inferred only
- OPRM1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35372|GO:0070374Inferred only
- OR2AT4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology A6NND4|GO:0070374Inferred only
- P2RY1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P47900|GO:0070374Inferred only
- P2RY6 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q15077|GO:0070374Inferred only
- PDE8A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O60658|GO:0070374Inferred only
- PDE8B regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O95263|GO:0070374Inferred only
- PDGFA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P04085|GO:0070374Inferred only
- PDGFB regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01127|GO:0070374Inferred only
- PDGFC regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NRA1|GO:0070374Inferred only
- PDGFD regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9GZP0|GO:0070374Inferred only
- PDGFRA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P16234|GO:0070374Inferred only
- PDGFRB regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P09619|GO:0070374Inferred only
- PHB1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P35232|GO:0070374Inferred only
- PHB2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q99623|GO:0070374Inferred only
- PLA2G2A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P14555|GO:0070374Inferred only
- PLA2G5 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P39877|GO:0070374Inferred only
- PRKCA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P17252|GO:0070374Inferred only
- PRKCZ regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q05513|GO:0070374Inferred only
- PRKD2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9BZL6|GO:0070374Inferred only
- PRXL2C regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q7RTV5|GO:0070374Inferred only
- PTK2B regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q14289|GO:0070374Inferred only
- PTPN11 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q06124|GO:0070374Inferred only
- PTPN22 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9Y2R2|GO:0070374Inferred only
- PTPRC regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P08575|GO:0070374Inferred only
- PYCARD regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9ULZ3|GO:0070374Inferred only
- RAMP3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O60896|GO:0070374Inferred only
- RAP1A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P62834|GO:0070374Inferred only
- RAPGEF2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9Y4G8|GO:0070374Inferred only
- S100A7 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P31151|GO:0070374Inferred only
- SCIMP regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6UWF3|GO:0070374Inferred only
- SEMA7A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O75326|GO:0070374Inferred only
- SERPINF2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P08697|GO:0070374Inferred only
- SLAMF1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q13291|GO:0070374Inferred only
- SLC30A10 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q6XR72|GO:0070374Inferred only
- SPRY2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O43597|GO:0070374Inferred only
- SRC regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P12931|GO:0070374Inferred only
- TEK regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q02763|GO:0070374Inferred only
- TGFB1 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01137|GO:0070374Inferred only
- THPO regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P40225|GO:0070374Inferred only
- TIRAP regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P58753|GO:0070374Inferred only
- TMEM219 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q86XT9|GO:0070374Inferred only
- TNF regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P01375|GO:0070374Inferred only
- TNFAIP8L3 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q5GJ75|GO:0070374Inferred only
- TNFRSF11A regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9Y6Q6|GO:0070374Inferred only
- TNFSF11 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology O14788|GO:0070374Inferred only
- TREM2 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9NZC2|GO:0070374Inferred only
- TRPV4 regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology Q9HBA0|GO:0070374Inferred only
- VEGFA regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P15692|GO:0070374Inferred only
- VEGFB regulates positive regulation of ERK1 and ERK2 cascadeProteingene ontology P49765|GO:0070374Inferred only