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Proteins/UNIPROT:Q9NPH9
May play a role in local mechanisms of mucosal immunity and seems to have a pro-inflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin..
Function from UniProtKB (Q9NPH9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
20 statements
20 statements · 4 reference databases · Subject: IL26 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
3 names
Resolves to: IL26