Proteins/UNIPROT:Q9H706

GAREM1

ProteinUNIPROT:Q9H706

[Isoform 1]: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation..

Function from UniProtKB (Q9H706), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 2 reference databases · Subject: GAREM1 · Sources: gene ontology, Hetionet

Order

GRIN1 covaries with GAREM1ProteinHetionet hetionet:covaries:2902-64762Inferred only
CRKL interacts with GAREM1ProteinHetionet hetionet:interacts:1399-64762Inferred only
GRB2 interacts with GAREM1ProteinHetionet hetionet:interacts:2885-64762Inferred only
GAREM1 regulates positive regulation of cell population proliferationBiological processgene ontology Q9H706|GO:0008284Inferred only
GAREM1 regulates positive regulation of ERK1 and ERK2 cascadeBiological processgene ontology Q9H706|GO:0070374Inferred only
ESPL1 increases the expression of GAREM1ProteinHetionet hetionet:regulates:9700-64762Inferred only
IKBKG decreases the expression of GAREM1ProteinHetionet hetionet:regulates:8517-64762Inferred only
MACF1 increases the expression of GAREM1ProteinHetionet hetionet:regulates:23499-64762Inferred only
PSMA1 increases the expression of GAREM1ProteinHetionet hetionet:regulates:5682-64762Inferred only
PSMD2 increases the expression of GAREM1ProteinHetionet hetionet:regulates:5708-64762Inferred only
RRP8 increases the expression of GAREM1ProteinHetionet hetionet:regulates:23378-64762Inferred only
TGDS increases the expression of GAREM1ProteinHetionet hetionet:regulates:23483-64762Inferred only

Other names

5 names

Resolves to: GAREM1

Also called: C18orf11FAM59AGAREMGRB2-associated and regulator of MAPK protein 1GRB2-associated and regulator of MAPK1

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