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Proteins/UNIPROT:O95263
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland.
Function from UniProtKB (O95263), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
23 statements
23 statements · 9 reference databases · Subject: PDE8B · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
2 names
Resolves to: PDE8B
Human-GEM MAR04014CC BY 4.0Reference data
3',5'-cyclic GMP+waterGMP+proton
Catalysed by PDE8A or PDE6C or PDE10A or PDE8B or PDE4D or PDE1A or PDE1B or PDE11A or PDE6A or PDE6B or PDE5A or PDE6H and 7 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.17, 3.1.4.35cytosol
Human-GEM MAR04048CC BY 4.0Reference data
3',5'-cyclic AMP+waterAMP+proton
Catalysed by PDE4A or PDE8A or PDE4C or PDE10A or PDE8B or PDE4D or PDE1A or PDE1B or PDE11A or PDE6H or PDE3B or PDE1C and 6 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.17Golgi apparatus
Human-GEM MAR08087CC BY 4.0Reference data
3',5'-cyclic AMP+waterAMP+hydron
Catalysed by PDE2A or PDE8A or PDE8B or ENPP1 or PDE4A or PDE1A or PDE1B or PDE4B or PDE4C or PDE4D or PDE3B or PDE7A and 6 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:25277CC BY 4.0Reference data