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Proteins/UNIPROT:P09038
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation..
Function from UniProtKB (P09038), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
209 statements
209 statements · 4 reference databases · Subject: FGF2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
6 names
Resolves to: FGF2