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Proteins/UNIPROT:P85298

ARHGAP8

Protein·UNIPROT:P85298

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GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state..

Function from UniProtKB (P85298), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

11 statements

11 statements · 3 reference databases · Subject: ARHGAP8 · Sources: gene ontology, Hetionet, Reactome

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ARHGAP1 interacts with ARHGAP8ProteinHetionet hetionet:interacts:23779-392Inferred only
BNIP2 interacts with ARHGAP8ProteinHetionet hetionet:interacts:23779-663Inferred only
SH3GL1 interacts with ARHGAP8ProteinHetionet hetionet:interacts:23779-6455Inferred only
ARHGAP8 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ARHGAP8 participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ARHGAP8 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ARHGAP8 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ARHGAP8 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
ARHGAP8 regulates negative regulation of endocytic recyclingBiological processgene ontology P85298|GO:2001136Inferred only
ARHGAP8 regulates positive regulation of ERK1 and ERK2 cascadeBiological processgene ontology P85298|GO:0070374Inferred only
ARHGAP8 regulates regulation of small GTPase mediated signal transductionBiological processgene ontology P85298|GO:0051056Inferred only

Other names

2 names

Resolves to: ARHGAP8

Also called: Rho GTPase-activating protein 8Rho-type GTPase-activating protein 8

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