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Proteins/UNIPROT:P25713

MT3

Protein·UNIPROT:P25713

Open in the graph

Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.

Function from UniProtKB (P25713), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

20 statements

20 statements · 4 reference databases · Subject: MT3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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BEND6 covaries with MT3ProteinHetionet hetionet:covaries:221336-4504Inferred only
RWDD2A covaries with MT3ProteinHetionet hetionet:covaries:112611-4504Inferred only
MT3 interacts with TERF2IPProteinHetionet hetionet:interacts:4504-54386Inferred only
MT3 interacts with TTRProteinHetionet hetionet:interacts:4504-7276Inferred only
MT3 participates in Cellular responses to stimuliPathwayReactome R-HSA-8953897Inferred only
MT3 participates in Copper homeostasisPathwayWikiPathways WP3286Inferred only
MT3 participates in Metallothioneins bind metalsPathwayReactome R-HSA-5661231Inferred only
MT3 participates in Response to metal ionsPathwayReactome R-HSA-5660526Inferred only
MT3 participates in Zinc homeostasisPathwayWikiPathways WP3529Inferred only
MT3 regulates negative regulation of axon extensionBiological processgene ontology P25713|GO:0030517Inferred only
MT3 regulates negative regulation of cell growthBiological processgene ontology P25713|GO:0030308Inferred only
MT3 regulates negative regulation of hydrogen peroxide catabolic processBiological processgene ontology P25713|GO:2000296Inferred only

Show the remaining 8

MT3 regulates negative regulation of neuron apoptotic processBiological processgene ontology P25713|GO:0043524Inferred only
MT3 regulates negative regulation of neuron projection developmentBiological processgene ontology P25713|GO:0010977Inferred only
MT3 regulates negative regulation of oxidoreductase activityBiological processgene ontology P25713|GO:0051354Inferred only
MT3 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology P25713|GO:0045893Inferred only
MT3 regulates positive regulation of ERK1 and ERK2 cascadeBiological processgene ontology P25713|GO:0070374Inferred only
MT3 regulates positive regulation of gene expressionBiological processgene ontology P25713|GO:0010628Inferred only
MT3 regulates positive regulation of protein phosphorylationBiological processgene ontology P25713|GO:0001934Inferred only
MT3 regulates positive regulation of vascular endothelial growth factor receptor signaling pathwayBiological processgene ontology P25713|GO:0030949Inferred only

Other names

6 names

Resolves to: MT3

Also called: GIFGIFBGrowth inhibitory factorMetallothionein-IIIMT-3MT-III

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