a 1-O-alkyl-2-acetyl-sn-glycerol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

143 compounds within 3 steps: 3 in 1, 27 in 2, 113 in 3

Three steps

cadaverineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-acetylcadaverine + H2O = cadaverine + acetate
3. N-acetylcadaverine + H2O = cadaverine + acetate
Catalysed by NCEH1, HDAC10
(3S)-citramalyl-CoAReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (3S)-citramalyl-CoA = pyruvate + acetyl-CoA
Catalysed by NCEH1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosol
an S-substituted L-cysteineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
Catalysed by NCEH1, ACY3
D-glucosamine 6-phosphateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
3. D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)
Catalysed by NCEH1, AMDHD2, GNPNAT1One of 2 routes
CDP-cholineReach from here →
1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
2. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)
3. phosphocholine + CTP + H(+) = CDP-choline + diphosphate
Catalysed by CHPT1, CEPT1, ENPP7, PCYT1A and 1 morecytosolOne of 2 routes
5-amino-2-oxopentanoateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine
Catalysed by NCEH1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosol
(4R)-4-hydroxy-2-oxoglutarateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by NCEH1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosol
a 1-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine
Catalysed by NCEH1, ASAH1, PLA2G15
a 1-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by NCEH1, ASAH1, PLA2G15
1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)
Catalysed by NCEH1, ASAH1, PLA2G15
a 2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 2-acyl-sn-glycero-3-phosphoethanolamine
Catalysed by NCEH1, ASAH1, PLA2G15
a 2-acyl-sn-glycero-3-phospho-L-serineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
2-acetamido-2-deoxy-D-glucopyranose 1-phosphateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate
3. phosphoglucomutase (N-acetylglucosamine-6-phosphate)
Catalysed by NCEH1, AMDHD2, PGM3cytosol
(4S)-4-hydroxy-2-oxoglutarateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Catalysed by NCEH1, SLC16A4, SLC16A5, SLC16A3 and 3 moreextracellular space, cytosol
1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
1-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase
2. a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine
3. 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)
Catalysed by CHPT1, CEPT1, LCAT, PLA2G7cytosolOne of 5 routes
1-hexadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine
Catalysed by NCEH1, ASAH1, PLA2G15One of 3 routes
a 1-O-alkylglycerone 3-phosphateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. a 1-O-alkyl-sn-glycerol + ATP = a 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+)
3. a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) = a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)
Catalysed by NCEH1, DGKA, DGKQ, DGKZ and 1 more
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 3 routes
4-acetamidobutanalReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-acetylputrescine + H2O = putrescine + acetate
3. N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)
Catalysed by NCEH1, HDAC10, AOC2, AOC1 and 3 morecytosolOne of 2 routes
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 9 routes
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 2 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 3 routes
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 3 routes
1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
a 1-O-alkyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. a 1-O-alkyl-sn-glycerol + ATP = a 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+)
3. a 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)
Catalysed by NCEH1, DGKA, DGKQ, DGKZ and 1 more
16alpha,17alpha-dihydroxyprogesteroneReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. cytochrome P450 (17alpha-hydroxyprogesterone)
3. 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by NCEH1, CYP17A1endoplasmic reticulum
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine
Catalysed by NCEH1, ASAH1, PLA2G15
1-octadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by NCEH1, ASAH1, PLA2G15
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by NCEH1, ASAH1, PLA2G15One of 8 routes
N-(acetyl)-sphing-4-enine-1-phosphateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by NCEH1, ASAH1, CERK
2-(1-hydroxyethyl)thiamine diphosphateReach from here →
1. a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = a 1-O-alkyl-sn-glycerol + acetate + H(+)
2. transport of acetate and pyruvate (cytosol to extracellular)
3. pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by NCEH1, SLC16A4, SLC16A5, SLC16A3 and 5 moreextracellular space, cytosol, mitochondrial matrix