2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

436 compounds within 3 steps: 9 in 1, 87 in 2, 340 in 3

One step

Two steps

(S)-carnitineReach from here →
1. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. Utilized Transport
Catalysed by PLA2G6, ASPGendoplasmic reticulum, cytosolOne of 2 routes
(14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PLA2G6, ASPG, CYP1A1 and 6 more

, CYP1A2

(14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 6 more

(11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP2C8, CYP2C9 and 3 more

(11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP2C8 and 5 more

(8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP2C9, CYP2J2

(8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP2D6 and 4 more

5,6-epoxy-(8Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 24 morecytosolOne of 4 routes

17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

16-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1

10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP3A4, CYP2C9

(8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, ALOX15

(14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, ALOX15

2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by PLA2G6, ASPG, SLCO1B1extracellular space, cytosolOne of 2 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →

Catalysed by PLA2G6, ASPG, PM20D1

7-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 24 morecytosolOne of 2 routes

13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP2C9

16(R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPG, CYP1A1, CYP1A2 and 24 morecytosol

2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →

Catalysed by PTGS2

1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →

Catalysed by LPGAT1, ALOX15B

8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by PLA2G6, ASPGcytosolOne of 2 routes

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serineReach from here →

Catalysed by PLA2G6, ASPG, FAAH, PM20D1

cholineReach from here →

Catalysed by PLA2G6, ASPG, GPCPD1cytosolOne of 3 routes

arachidonoyl-CoAReach from here →

Catalysed by PLA2G6, ASPG, SLC27A2, ACSL4 and 6 morecytosolOne of 3 routes

12(S)-HPETEReach from here →

Catalysed by PLA2G6, ASPG, ALOX12cytosolOne of 4 routes

15(S)-HPETEReach from here →

Catalysed by PLA2G6, ASPG, ALOX15B, ALOX15cytosolOne of 4 routes

5(S)-HPETEReach from here →

Catalysed by PLA2G6, ASPG, ALOX5cytosol

betaine aldehydeReach from here →

Catalysed by PTGS2, CHDH

CHEBI:15978Reach from here →

Catalysed by PLA2G6, ASPG, GPCPD1cytosol

oxaloacetateReach from here →

Catalysed by PTGS2, D2HGDH

formaldehydeReach from here →

Catalysed by PTGS2, KDM1A, KDM1BOne of 3 routes

CHEBI:16856Reach from here →

Catalysed by PLA2G6, ASPGextracellular space, cytosolOne of 2 routes

all-trans-retinolReach from here →

Catalysed by PTGS2, RETSAT

AH2Reach from here →

Catalysed by PTGS2, AIFM1, PYROXD1One of 19 routes

L-cysteineReach from here →

Catalysed by PTGS2, MOCOS

glycerolReach from here →

Catalysed by PLA2G6, ASPG, ENPP6

CHEBI:18132Reach from here →

Catalysed by PLA2G6, ASPG, ENPP6cytosol

O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronateReach from here →

Catalysed by PLA2G6, ASPG, UGT1A9, UGT2B7 and 4 more

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →

Catalysed by PLA2G6, ASPG, FAAHcytosol

phosphocholineReach from here →

Catalysed by PLA2G6, ASPG, ENPP6