Compound

2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine

A lysophosphatidylcholine 18:2 in which the acyl group is specified as linoleoyl and is located at position 2.

Definition from ChEBI (CHEBI:76084), read 2026-09-23. CC BY 4.0.

CHEBI:76084ChEBI

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Structure

2D depiction

Class: Organic compound
Formula: C26H50NO7P
Mass: 519.66 g/mol
Charge: 0
InChIKey: LSUXCWJOIAWGOU-FTJOPAKQSA-N
SMILES: CCCCC/C=CC/C=CCCCCCCCC(=O)O[C@H](CO)COP(=O)([O-])OCC[N+](C)(C)C
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Chemical structure

2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine has the functional parent linoleic acidCompoundChEBI CHEBI:76084Inferred only

Statements

2 statements

2 statements · 1 reference database · Subject: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine · Sources: Rhea

Order

2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine is a substrate of LPGAT1ProteinRhea RHEA:74803Inferred only
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine is a substrate of TAFAZZINProteinRhea RHEA:68988Inferred only

Reactions

8 reactions

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+N-(acetyl)-sphing-4-enine2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by PLA2G15
Reaction pageLeft to rightBalanced
Rhea RHEA:38811CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+water2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+hexadecanoate+hydron
Catalysed by PLAAT3 or PLB1
Reaction pageLeft to rightBalanced
Rhea RHEA:40971CC BY 4.0Reference data
1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+water2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+tetradecanoate+hydron
Catalysed by ABHD3
Reaction pageLeft to rightBalanced
Rhea RHEA:54388CC BY 4.0Reference data
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+water2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+octadecanoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:56636CC BY 4.0Reference data
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+water2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+(9Z,12Z)-octadecadienoate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:56640CC BY 4.0Reference data
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+N-(acetyl)-sphing-4-enine1-octadecanoyl-N-(acetyl)-sphing-4-enine+2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine
Reaction pageDirection not assertedBalanced
Rhea RHEA:57112CC BY 4.0Reference data
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1-hexadecanoyl-sn-glycero-3-phosphocholine2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by TAFAZZIN
Reaction pageReversibleBalanced
Rhea RHEA:68988CC BY 4.0Reference data
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+octadecanoyl-CoA1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPGAT1
Reaction pageDirection not assertedBalanced
Rhea RHEA:74803CC BY 4.0Reference data

Other names

5 names

Resolves to: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine

Also called: 2-linoleoyllysophosphatidylcholineLPC[0:0/18:2(omega-6)]LPC[0:0/18:2(ω-6)]PC(0:0/18:2(9Z,12Z))
Systematic name: (2R)-3-hydroxy-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylazaniumyl)ethyl phosphate