CHEBI:16264

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

45 compounds within 3 steps: 3 in 1, 8 in 2, 34 in 3

One step

a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
1. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)
Catalysed by B3GNT5cytosolOne of 2 routes
aldehydo-N-acetyl-D-mannosamineReach from here →
1. UDP-N-acetyl-D-glucosamine 2-epimerase
Catalysed by GNEendoplasmic reticulumOne of 2 routes
a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →
1. phosphatidylinositol N-acetylglucosaminyltransferase (PI pool)
Catalysed by PIGA, PIGP, PIGH, PIGY and 3 moreendoplasmic reticulumOne of 2 routes

Two steps

Three steps

B3GALT2

, B3GALT5

, B3GALT1

cytosol

One of 3 routes

aceneuramateReach from here →

Catalysed by GNE, NPLendoplasmic reticulum

acetateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 4 moreendoplasmic reticulumOne of 3 routes

N-acetyl-beta-neuraminic acidReach from here →

Catalysed by GNE, NPLendoplasmic reticulum, cytosol

N-acetyl-D-glucosamineReach from here →

Catalysed by GNE, RENBPendoplasmic reticulum, cytosol

a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 4 moreendoplasmic reticulumOne of 3 routes

aldehydo-N-acetyl-D-mannosamine 6-phosphateReach from here →

Catalysed by GNEendoplasmic reticulum, cytosolOne of 2 routes

Catalysed by PIGA, PIGP, PIGH, PIGY and 8 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

N-acetylcadaverineReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

acetoacetateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 9 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

a phenyl acetateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 7 moreendoplasmic reticulum

a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E))Reach from here →

Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 1 morecytosol

a 2-acyl-6-alpha-D-glucosaminyl-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

acetylpyruvateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

pyruvateReach from here →

Catalysed by GNE, NPLendoplasmic reticulum, cytosolOne of 4 routes

all-trans-retinoic acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 7 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

phosphatidic acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

N(2)-acetyl-L-ornithineReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum, cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 8 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

17alpha-hydroxyprogesteroneReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

4-methylumbelliferyl acetateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 7 moreendoplasmic reticulum

N-acetylneuraminate 9-phosphateReach from here →

Catalysed by GNE, NANSendoplasmic reticulum, cytosolOne of 2 routes

a 2-hexadecanoyl-6-alpha-D-glucosaminy-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →

Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 3 morecytosol

alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →

Catalysed by B3GNT5, B3GALT2, B3GALT5, B3GALT1 and 2 morecytosolOne of 2 routes

17alpha-hydroxypregnenoloneReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

N-glycoloylneuraminateReach from here →

Catalysed by GNE, NPLendoplasmic reticulum, cytosol

formic acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 7 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

propionic acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 8 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

butyric acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 8 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

(S)-lactic acidReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 10 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

N-(acetyl)-sphing-4-enineReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

N-acetyl-D-glucosamine 6-phosphateReach from here →

Catalysed by GNE, RENBP, NAGKendoplasmic reticulum, cytosolOne of 3 routes

CMP-N-acetyl-beta-neuraminateReach from here →

Catalysed by GNE, NPL, CMASendoplasmic reticulum, cytosol, nucleusOne of 2 routes

N-acetylputrescineReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

N(8)-acetylspermidineReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))Reach from here →

Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosolOne of 2 routes

an N-acetyl-L-cysteine-S-conjugateReach from here →

Catalysed by PIGA, PIGP, PIGH, PIGY and 5 moreendoplasmic reticulum

beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamineReach from here →

Catalysed by GNE, RENBP, B4GALT3, B4GALT4 and 2 moreendoplasmic reticulum, cytosol

a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →

Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosol