dihydroxyacetone

Three steps

• CHEBI:17312Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N1,N12-diacetylspermine to N1-acetylspermine conversion

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, cytosolOne of 2 routes

• D-glyceraldehydeReach from here →
  1. dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)
  2. D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate
  3. D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)

  Catalysed by TKFC, TPI1One of 2 routes

• L-cysteineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N-acetylglutamate synthase (N-acetyl-L-cysteine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrix

• (7Z,10Z,13Z)-hexadecatrienoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrix

• CHEBI:17797Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. transketolase (D-xylulose-5-phosphate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, cytosolOne of 2 routes

• CHEBI:17927Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N1,N8-diacetylspermidine to N1-acetylspermidine conversion

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, cytosol

• (5Z)-dodecenoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. acetyl-CoA C-acyltransferase (3-oxomyrist-7-enoyl-CoA)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 2 routes

• (11Z)-docosenoyl-CoA(4-)Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (cis-cetoleic acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 5 routes

• (7Z)-tetradecenoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase ((7Z)-tetradecenoic acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 8 routes

• (4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Fatty Acid Beta Oxidation (C18:4->C16:4), Mitochondrial

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 3 routes

• (7Z,10Z)-hexadecadienoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Fatty Acid Beta Oxidation Trans (C18:2->C16:2), Mitochondrial

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrix

• (4Z,7Z)-decadienoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Fatty Acid Beta Oxidation (C12:3->C10:2), Mitochondrial

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 2 routes

• (5Z)-octenoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Fatty Acid Beta Oxidation (C10:2->C8:1), Mitochondrial

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 2 routes

• CHEBI:27540Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. medium-chain acyl-CoA ligase (hexanoic acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 7 moreextracellular space, peroxisome, cytosolOne of 6 routes

• hydroxyacetoneReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
  3. aldose reductase (methylglyoxal)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 3 moreextracellular space, cytosolOne of 2 routes

• elaidic acidReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (elaidate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 5 routes

• beta-D-fructoseReach from here →
  1. dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)
  2. beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate
  3. beta-D-fructose + ATP = beta-D-fructose 1-phosphate + ADP + H(+)

  Catalysed by TKFC, ALDOB, KHK

• CHEBI:28701Reach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Propanoyl-CoA:acetyl-CoA C-acyltransferase

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisomeOne of 7 routes

• fatty acidReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. Acyl-CoA:glycerone-phosphate O-acyltransferase
  3. alkylglycerone phosphate synthase (acylglycerone-phosphate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, cytosol, peroxisome

• D-fructoseReach from here →
  1. dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)
  2. beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate
  3. beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate

  Catalysed by TKFC, ALDOB, IMPA1, DCPH1

• taurineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. bile acid-CoA:amino acid N-acyltransferase (taurodeoxycholate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, cytosolOne of 2 routes

• glycineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. glycine N-acyltransferase (N-arachidonoylglycine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 10 routes

• (R)-methylmalonyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. aldehyde dehydrogenase (2-methyl-3-oxopropanoate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrixOne of 2 routes

• (S)-methylmalonyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. (S)-methylmalonyl-CoA hydrolase

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, mitochondrial matrix

• 3'-dephospho-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. acid phosphatase 2, lysosomal (CoA)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, lysosomeOne of 2 routes

• (2E)-dodecenoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. (2E)-dodecenoyl-CoA formation

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, mitochondrial matrixOne of 3 routes

• 4,8,12-trimethyltridecanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. propanoyl-CoA C-acyltransferase (3-ketopristanoyl-CoA)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 3 moreextracellular space, peroxisomeOne of 2 routes

• (6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (gamma-linolenate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 7 routes

• butanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Butanoate:CoA ligase (AMP-forming)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 7 moreextracellular space, peroxisome, cytosolOne of 9 routes

• dodecanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (lauric acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 9 routes

• glutaryl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Production of Glutaryl Carnitine

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, cytosolOne of 2 routes

• eicosanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (eicosanoate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 12 routes

• itaconyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Itaconate:CoA ligase (GDP-forming)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 4 moreextracellular space, peroxisome, mitochondrial matrixOne of 2 routes

• (9Z,12Z)-octadecadienoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 13 routes

• tetradecanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (myristic acid)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 9 moreextracellular space, peroxisome, cytosolOne of 11 routes

• octanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. Octanoyl-CoA:L-carnitine O-octanoyltransferase

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrixOne of 20 routes

• phytanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. phytanate-CoA ligase

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, cytosolOne of 5 routes

• octadecanoyl-CoAReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. long-chain-fatty-acid-CoA ligase (stearate)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 8 moreextracellular space, peroxisome, cytosolOne of 15 routes

• (R)-S-lactoylglutathioneReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
  3. (R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, cytosolOne of 2 routes

• N-acetyl-D-glucosamine 6-phosphateReach from here →
  1. beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate
  2. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  3. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase

  Catalysed by DCPH1, GNPDA1, GNPDA2, GNPNAT1cytosol

• 1-hexadecanoyl-sn-glycero-3-phosphateReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase
  3. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 6 moreextracellular space, cytosolOne of 2 routes

• a long-chain fatty acidReach from here →
  1. dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)
  2. dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA
  3. a long chain fatty alcohol + a 1-acylglycerone 3-phosphate = a 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)

  Catalysed by TKFC, GNPAT, AGPS

• (2R)-3-phospho-glyceroyl phosphateReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
  3. D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 3 moreextracellular space, cytosolOne of 2 routes

• sphing-4-enineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. acyl-CoA:sphingosine N-acyltransferase

  Catalysed by ALPL, ALPP, ALPI, ALPG and 5 moreextracellular space, peroxisome, Golgi apparatusOne of 2 routes

• spermidineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. diamine N-acetyltransferase (N1-acetylspermidine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 3 moreextracellular space, peroxisome, cytosolOne of 3 routes

• L-methionineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N-acetylglutamate synthase (N-acetylmethionine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrix

• L-alanineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 1 moreextracellular space, peroxisome, mitochondrial matrix

• L-asparagineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N-acetylglutamate synthase (N-acetyl-L-asparagine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrix

• glycerol 2-phosphateReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase
  3. Formation of Glycerol-3-Phosphate

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, cytosol

• L,L-cystathionineReach from here →
  1. Glycerone phosphate phosphohydrolase
  2. glyceronephosphate O-acyltransferase (DHAP)
  3. N-acetylglutamate synthase (N-acetyl-L-cystathionine)

  Catalysed by ALPL, ALPP, ALPI, ALPG and 2 moreextracellular space, peroxisome, mitochondrial matrix