Compound
D-fructose
A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C6H12O6
- Mass
- 180.156 g/mol
- Charge
- 0
- InChIKey
- RFSUNEUAIZKAJO-VRPWFDPXSA-N
- SMILES
- OC[C@H]1OC(O)(CO)[C@@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- HK1ProteinUNIPROT:P19367substrate ofInferred only34 paths34 endpoints
- GCKProteinUNIPROT:P35557substrate ofInferred only30 paths30 endpoints
- HK2ProteinUNIPROT:P52789substrate ofInferred only25 paths25 endpoints
- HK3ProteinUNIPROT:P52790substrate ofInferred only22 paths22 endpoints
- SLC2A5ProteinUNIPROT:P22732transported byInferred only9 paths8 endpoints
- SLC2A2ProteinUNIPROT:P11168transported byInferred only6 paths5 endpoints
- SLC2A8ProteinUNIPROT:Q9NY64transported byInferred only2 paths2 endpoints
What the reference databases state
Chemical structure
- D-fructose 6-phosphate has the functional parent D-fructoseCompoundChEBI CHEBI:61527Inferred only
Statements
18 statements
18 statements · 1 reference database · Subject: D-fructose · Sources: Rhea
- beta-D-fructose 1-phosphate is converted to D-fructoseCompoundRhea RHEA:35603Inferred only
- D-fructose 6-phosphate is converted to D-fructoseCompoundRhea RHEA:28558Inferred only
- D-fructose is converted to D-fructose 6-phosphateCompoundRhea RHEA:28558Inferred only
- D-fructose is converted to D-fructose 6-phosphateCompoundRhea RHEA:16125Inferred only
- D-mannitol is converted to D-fructoseCompoundRhea RHEA:16765Inferred only
- D-fructose is converted to D-mannitolCompoundRhea RHEA:12084Inferred only
- D-fructose is converted to D-mannitolCompoundRhea RHEA:16765Inferred only
- D-mannitol is converted to D-fructoseCompoundRhea RHEA:12084Inferred only
- D-mannose is converted to D-fructoseCompoundRhea RHEA:22604Inferred only
- D-fructose is converted to D-mannoseCompoundRhea RHEA:22604Inferred only
- D-fructose is a substrate of GCKProteinRhea RHEA:16125Inferred only
- D-fructose is a substrate of HK1ProteinRhea RHEA:16125Inferred only
Show the remaining 6
- D-fructose is a substrate of HK2ProteinRhea RHEA:16125Inferred only
- D-fructose is a substrate of HK3ProteinRhea RHEA:16125Inferred only
- D-fructose is transported by SLC2A2ProteinRhea RHEA:60372Inferred only
- D-fructose is transported by SLC2A5ProteinRhea RHEA:60372Inferred only
- D-fructose is transported by SLC2A7ProteinRhea RHEA:60372Inferred only
- D-fructose is transported by SLC2A8ProteinRhea RHEA:60372Inferred only
Reactions
22 reactions
D-mannitol+NAD(1-)D-fructose+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:12084CC BY 4.0Reference data
D-fructose+NADP(3-)CHEBI:17011+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14069CC BY 4.0Reference data
D-fructose+ATP(4-)D-fructose 6-phosphate+ADP(3-)+hydron
Catalysed by HK1 or GCK or HK2 or HK3
Reaction pageLeft to rightBalanced
Rhea RHEA:16125CC BY 4.0Reference data
CHEBI:76533+D-fructosea ribonucleoside 5'-diphosphate+sucrose+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16241CC BY 4.0Reference data
D-mannitol+NADP(3-)D-fructose+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:16765CC BY 4.0Reference data
D-mannitol+2Fe(III)-[cytochrome c]D-fructose+2Fe(II)-[cytochrome c]+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:17597CC BY 4.0Reference data
[(1->6)-alpha-D-glucosyl](n)+sucrose[(1->6)-alpha-D-glucosyl](n+1)+D-fructose
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:18825CC BY 4.0Reference data
D-fructose+D-glucoseD-glucono-1,5-lactone+D-glucitol
Reaction pageDirection not assertedBalanced
Rhea RHEA:20637CC BY 4.0Reference data
Reaction pageDirection not assertedBalanced
Rhea RHEA:22604CC BY 4.0Reference data
sucrose+hydrogenphosphateD-fructose+alpha-D-glucose 1-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:24048CC BY 4.0Reference data
[(1->4)-alpha-D-glucosyl](n)+sucrose[(1->4)-alpha-D-glucosyl](n+1)+D-fructose
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24572CC BY 4.0Reference data
D-fructose 6-phosphate+waterD-fructose+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:28558CC BY 4.0Reference data
Where it reaches
4 systems, 6 regions, 12 tissues, 15 transporter routes — routes, not measurements: transporters known to carry D-fructose are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: D-fructose
- Also called
- D-arabino-HexuloseFruit sugarLevulose
- Systematic name
- D-fructofuranose