oleoyl-CoA

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by FADS2, LPCAT3cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA

Catalysed by FADS2, LPCAT3cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA

Catalysed by FADS2, LPCAT3cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by FADS2, LPCAT3cytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 7 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 3 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by FADS2, LCLAT1cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by FADS2, LCLAT1cytosol

1. Beta Oxidation Fatty Acid
2. octanoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by ACADM, ACADS, LPCAT4mitochondrial matrix

1. Beta Oxidation Fatty Acid
2. octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA

Catalysed by ACADM, ACADS, LPCAT1mitochondrial matrix

1. acyl-CoA pool formation and breakdown
2. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA

Catalysed by MOGAT2, MOGAT1cytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA

Catalysed by FADS2, MOGAT2, MOGAT1cytosol

1. Beta Oxidation Fatty Acid
2. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by ACADM, ACADS, LCLAT1mitochondrial matrix

1. Beta Oxidation Fatty Acid
2. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by ACADM, ACADS, LCLAT1mitochondrial matrix

1. acyl-CoA pool formation and breakdown
2. 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA

Catalysed by MOGAT2, AWAT2cytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Activation of dodecanedioic acid

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Production of Sebacoylcarnitine

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Production of Suberylcarnitine

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Activation of adipic acid for Formation of Adipoyl Carnitine

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 4 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 8 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Production of 3-Hydroxyoctadecenoylcarnitinec

Catalysed by CPT1A, CPT1C, CPT1Bcytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 6 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal

Catalysed by CPT1A, CPT1C, CPT1B, CRAT and 1 morecytosol, peroxisomeOne of 3 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal

Catalysed by CPT1A, CPT1C, CPT1B, ACAA1 and 3 morecytosol, peroxisome

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Production of Hexadecanedioylcarnitine

Catalysed by CPT1A, CPT1C, CPT1BcytosolOne of 2 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA

Catalysed by FADS2, AGPAT4cytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. fatty-acid-CoA ligase

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2cytosolOne of 2 routes

1. acyl-CoA pool formation and breakdown
2. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA

Catalysed by MOGAT1cytosolOne of 2 routes

1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA

Catalysed by LPCAT2, LPCAT1cytosol

1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by LPCAT4cytosol

1. Beta Oxidation Fatty Acid
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by ACADM, ACADS, LPCAT4mitochondrial matrix

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. medium-chain acyl-CoA ligase (undecylic acid)

Catalysed by CPT1A, CPT1C, CPT1B, ACSM4 and 5 morecytosolOne of 3 routes

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

Catalysed by FADS2, ACADL, ACADVL, ACAD9cytosol

1. Oleoyl-CoA hydrolase
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate

Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 6 morecytosol

1. Oleoyl-CoA hydrolase
2. (9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 3 morecytosol

1. Oleoyl-CoA hydrolase
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)

Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 2 morecytosol

1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA

Catalysed by FADS2, HADHAcytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (physeteric acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 9 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial

Catalysed by CPT1A, CPT1C, CPT1B, ACADM and 3 morecytosol, mitochondrial matrix

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)

Catalysed by CPT1A, CPT1C, CPT1B, HADHA and 2 morecytosol, mitochondrial matrix

1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)

Catalysed by GLYATL1B, GLYATL1cytosol

1. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
2. hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex

Catalysed by ACADM, ACADL, ACADVL, ACAD9 and 1 moremitochondrial matrixOne of 3 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 9 routes

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)

Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 7 morecytosolOne of 5 routes

1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA

Catalysed by ACAA1, SCP2, ACAA2, HADHBcytosol

1. Transport of octadecenoyl-CoA into Mitochondrial Matrix
2. glycine N-acyltransferase (N-arachidonoylglycine)
3. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine

Catalysed by CPT1A, CPT1C, CPT1B, GLYAT and 3 morecytosol, mitochondrial matrixOne of 2 routes

1. Acyl-CoA:cholesterol O-acyltransferase
2. Steryl-ester acylhydrolase
3. cytochrome P450 (cholesterol)